Primate Monocytes - CD14, CD16 - Ziegler-Heitbrock


Increased Classical Monocytes in South Asians Compared to White Caucasians at Risk for Coronary Atherosclerosis.


South Asian (SA) individuals have an increased prevalence of coronary artery disease (CAD) and myocardial infarction compared with age- and sex-adjusted White Caucasian (WC) individuals. The mechanisms behind this remain unclear. Although classical CD14++CD16− monocytes have been shown to act as independent predictors of cardiovascular disease in humans, 1, 2, 3 differences in the distribution of monocyte subsets have not been established in SA and WC individuals. The goal of this study was to determine whether there is an independent association of SA ethnicity with the distribution of monocyte subsets.

Authors: Hosseini F, Franco C, Whalen BA, Taylor CM, Sellers SL, Khan N, Kaila K, Bainey K, Farkouh M, Gupta M, Verma S, Ramanathan K,
Journal: Can J Cardiol;2023, 39, 1584. doi:10.1016/j.cjca.2023.07.028
Year: 2023
PubMed: PMID: 37517476 (Go to PubMed)