Primate Monocytes - CD14, CD16 - Ziegler-Heitbrock


Increased transmigration of intermediate monocytes associated with atherosclerotic burden in people with HIV on antiretroviral therapy.


This study evaluated the association between the transmigration of monocyte subpopulations that contributes to atherosclerosis development, along with surrogate biomarkers of inflammation and atherosclerosis, through carotid intima-media thickness (cIMT) measurements of 72 people with HIV (PWH) on suppressive antiretroviral therapy (ART). We found that the transmigration of intermediate monocytes was positively correlated with D-dimer and cIMT, suggesting that intermediate monocytes may have a greater propensity to promote cardiovascular disease (CVD) in PWH on ART.

Authors: Chow DC, Saiki KMW, Siriwardhana C, Lozano-Gerona J, Vanapruks S, Ogle J, Premeaux TA, Ndhlovu LC, Boisvert WA,
Journal: AIDS;2023 Jun 1;37(7):1177-1179. doi:10.1097/QAD.0000000000003534
Year: 2023
PubMed: PMID: 36927653 (Go to PubMed)