Primate Monocytes - CD14, CD16 - Ziegler-Heitbrock


Altered monocytic phenotypes are linked to hypertension form - a clinical observational study.


The past decade witnessed an explosion of research interest in the role of immunity in hypertension. Accumulating evidence suggests that immune cells infiltrate the key organs contributing to target damage [1]. Although it has become evident that T cells play an important role in experimental and human hypertension [1–3], the role of monocytes subsets remains to be elucidated. In humans, elevated blood pressure (BP) is related to the increased levels of inflammatory cytokines and activated monocytes [4]. Our study aimed to examine the exact phenotype of monocyte subsets in relation to various clinical pictures — established hypertension (HTN) and secondary form — primary hyperaldosteronism (PHA), compared to newly diagnosed hypertensives (NDH).

Authors: Imiela AM, Siedliński M, Dobrowolski P, Pręgowska-Chwała B, Kabat M, Oliveira Silva RN, Koshy AM, Wróbel A, Cendrowska-Demkow I, Januszewicz M, Januszewicz A, Prejbisz A, Mikołajczyk TP,
Journal: Kardiol Pol;2022Feb07. doi:10.33963/KP.a2022.0036
Year: 2022
PubMed: PMID: 35129205 (Go to PubMed)