The anti-inflammatory effects of exercise: mechanisms and implications for the prevention and treatment of disease
Abstract
Regular exercise reduces the risk of chronic metabolic and cardiorespiratory diseases, in part because exercise exerts anti-inflammatory effects. However, these effects are also likely to be responsible for the suppressed immunity that makes elite athletes more susceptible to infections. The anti-inflammatory effects of regular exercise may be mediated via both a reduction in visceral fat mass (with a subsequent decreased release of adipokines) and the induction of an anti-inflammatory environment with each bout of exercise. In this Review, we focus on the known mechanisms by which exercise - both acute and chronic - exerts its anti-inflammatory effects, and we discuss the implications of these effects for the prevention and treatment of disease.
| Authors: | Gleeson M, Bishop NC, Stensel DJ, Lindley MR, Mastana SS, Nimmo MA |
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| Journal: | Nat Rev Immunol. 11(9):607-15. |
| Year: | 2011 |
| PubMed: | Find in PubMed |