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Literature Mono Mac 6

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Title
Journal
Year
Abstract
PubMed
Wójcik-Piotrowicz K, Kaszuba-Zwoińska J, Piszczek P, Nowak B, Guzdek P, Gil K, Rokita E,:
Low-frequency electromagnetic fields influence the expression of calcium metabolism related proteins in leukocytic cell lines.
Environ Toxicol Pharmacol;2023Nov19; 104 104320. doi:10.1016/j.etap.2023.104320
2023
Abstract PubMed
Wójcik-Piotrowicz K, Kaszuba-Zwoińska J, Piszczek P, Nowak B, Guzdek P, Gil K, Rokita E,:
Low-frequency electromagnetic fields influence the expression of calcium metabolism related proteins in leukocytic cell lines.
Environ Toxicol Pharmacol;2023Nov19; 104 104320. doi:10.1016/j.etap.2023.104320
2023
Abstract PubMed
Schepetkin IA, Danilets MG, Ligacheva AA, Trofimova ES, Selivanova NS, Sherstoboev EY, Krivoshchekov SV, Gulina EI, Brazovskii KS, Kirpotina LN, Quinn MT, Belousov MV,:
Immunomodulatory Activity of Polysaccharides Isolated from Saussurea salicifolia L. and Saussurea frolovii Ledeb.
Molecules;2023Sep16; 28 (18) . doi:10.3390/molecules28186655
2023
Abstract PubMed
Chory EJ, Wang M, Ceribelli M, Michalowska AM, Golas S, Beck E, Klumpp-Thomas C, Chen L, McKnight C, Itkin Z, Wilson KM, Holland D, Divakaran S, Bradner J, Khan J, Gryder BE, Thomas CJ, Stanton BZ,:
High-throughput approaches to uncover synergistic drug combinations in leukemia.
SLAS Discov; 2023 Jun;28(4):193-201. doi:10.1016/j.slasd.2023.04.004
2023
Abstract PubMed
Huszár B, Szolga R, Bősze S, Oláhné Szabó R, Simon A, Karaghiosoff K, Czugler M, Drahos L, Keglevich G.:
Synthesis and Anticancer Activity of Phosphinoylated and Phosphonoylated N-Heterocycles Obtained by the Microwave-Assisted Palladium Acetate-Catalyzed Hirao Reaction.
Chemistry;2023Sep15 202302465. doi:10.1002/chem.202302465
2023
Abstract PubMed
Finger V, Kucera T, Kafkova R, Muckova L, Dolezal R, Kubes J, Novak M, Prchal L, Lakatos L, Andrs M, Hympanova M, Marek J, Kufa M, Spiwok V, Soukup O, Mezeiova E, Janousek J, Nevosadova L, Benkova M, Kitson RRA, Kratky M, Bősze S, Mikusova K, Ha:
2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1.
Eur J Med Chem;2023Jul03; 258 115611. doi:10.1016/j.ejmech.2023.115611
2023
Abstract PubMed
Doering J, Basten S, Ecke M, Herbster M, Kirsch B, Halle T, Lohmann CH, Bertrand J, Aurich J,:
Surface integrity modification of CoCrMo alloy by deep rolling in combination with sub-zero cooling as potential implant application.
J Biomed Mater Res B Appl Biomater . 2023 Apr;111(4):946-957 doi:10.1002/jbm.b.35204
2023
Abstract PubMed
Brunken F, Senft T, Herbster M, Relja B, Bertrand J, Lohmann CH,:
CoNiCrMo Particles, but Not TiAlV Particles, Activate the NLRP3 Inflammasome in Periprosthetic Cells.
Int J Mol Sci;2023 Mar 7;24(6):5108. . doi:10.3390/ijms24065108
2023
Abstract PubMed
Ebert S, Zang L, Ismail N, Otabil M, Fröhlich A, Egea V, Ács S, Hoeberg M, Berres ML, Weber C, Moreira JMA, Ries C, Bernhagen J, El Bounkari O,:
Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation.
Cells;2023Jul20; 12 (14) . doi:10.3390/cells12141899
2023
Abstract PubMed
Ebert S, Zang L, Ismail N, Otabil M, Fröhlich A, Egea V, Ács S, Hoeberg M, Berres ML, Weber C, Moreira JMA, Ries C, Bernhagen J, El Bounkari O,:
Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation.
Cells;2023Jul20; 12 (14) . doi:10.3390/cells12141899
2023
Abstract PubMed
Bellini C, Vergara E, Bencs F, Fodor K, Bősze S, Krivić D, Bacsa B, Surguta SE, Tóvári J, Reljic R, Horváti K,:
Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection.
Bioconjug Chem;2023 Oct 18;34(10):1738-1753. doi:10.1021/acs.bioconjchem.3c00273
2023
Abstract PubMed
Bellini C, Vergara E, Bencs F, Fodor K, Bősze S, Krivić D, Bacsa B, Surguta SE, Tóvári J, Reljic R, Horváti K,:
Design and Characterization of a Multistage Peptide-Based Vaccine Platform to Target Mycobacterium tuberculosis Infection.
Bioconjug Chem;2023 Oct 18;34(10):1738-1753. doi:10.1021/acs.bioconjchem.3c00273
2023
Abstract PubMed
Schepetkin IA, Karpenko OS, Kovrizhina AR, Kirpotina LN, Khlebnikov AI, Chekal SI, Radudik AV, Shybinska MO, Quinn MT,:
Novel Tryptanthrin Derivatives with Selectivity as c-Jun N-Terminal Kinase (JNK) 3 Inhibitors.
Molecules; 2023 Jun 16;28(12):4806 . doi:10.3390/molecules28124806
2023
Abstract PubMed
Piszczek P, Wojcik-Piotrowicz K, Nowak B, Guzdek P, Novak P, Pytko-Polonczyk J, Gil K, Kaszuba-Zwoinska J,:
Phagocytosis of latex beads by a human monocytic Mono Mac 6 cell line and effects of low-frequency electromagnetic field interaction.
J Physiol Pharmacol;023, 74, 2, 235-247 doi:10.26402/jpp.2023.2.10
2023
Abstract PubMed
Nguyen MT, Hu Z, Mohammad M, Schöttler H, Niemann S, Schultz M, Barczyk-Kahlert K, Jin T, Hayen H, Herrmann M,:
Bacterial Lipoproteins Shift Cellular Metabolism to Glycolysis in Macrophages Causing Bone Erosion.
Microbiol Spectr;2023 Jun 15;11(3):e0429322.. doi:10.1128/spectrum.04293-22
2023
Abstract PubMed
Bruno JG, Sivils JC, Mohan S, Natarajan M,:
Alpha-thiol deoxynucleotide triphosphates (S-dNTPs) as radioprotective agents: A novel approach.
Biochem Biophys Res Commun; 2023 Jun 11;660:6-12. doi:10.1016/j.bbrc.2023.03.071
2023
Abstract PubMed
Bruno JG, Sivils JC, Mohan S, Natarajan M,:
Alpha-thiol deoxynucleotide triphosphates (S-dNTPs) as radioprotective agents: A novel approach.
Biochem Biophys Res Commun; 2023 Jun 11;660:6-12. doi:10.1016/j.bbrc.2023.03.071
2023
Abstract PubMed
Núñez Y, Garcia-León A, Falgàs A, Serna N, Sánchez-García L, Garrido A, Sierra J, Gallardo A, Unzueta U, Vázquez E, Villaverde A, Mangues R, Casanova I.:
T22-PE24-H6 Nanotoxin Selectively Kills CXCR4-High Expressing AML Patient Cells In Vitro and Potently Blocks Dissemination In Vivo.
Pharmaceutics; 2023 Feb 22;15(3):727. doi:10.3390/pharmaceutics15030727
2023
Abstract PubMed
Da Rocha MN, Guiot M, Nicod C, Trad R, Bouquet L, Haderbache R, Warda W, Baurand PE, Jouanneau C, Dulieu P, Deschamps M, Ferrand C,:
Coated recombinant target protein helps explore IL-1RAP CAR T-cell functionality in vitro.
Immunol Res; 2023 Apr;71(2):276-282 doi:10.1007/s12026-022-09348-y
2023
Abstract PubMed
Caslini C, Serna A,:
Telomere Transcription in MLL-Rearranged Leukemia Cell Lines: Increased Levels of TERRA Associate with Lymphoid Lineage and Are Independent of Telomere Length and Ploidy.
Biomedicines;2023Mar16; 11 (3) . doi:10.3390/biomedicines11030925
2023
Abstract PubMed
Coluccia A, Matti F, Zhu X, Lussi A, Stähli A, Sculean A, Eick S,:
In Vitro Study on Green Propolis as a Potential Ingredient of Oral Health Care Products.
Antibiotics (Basel);2022Dec06; 11 (12) . doi:10.3390/antibiotics11121764
2022
Abstract PubMed
Coluccia A, Matti F, Zhu X, Lussi A, Stähli A, Sculean A, Eick S,:
In Vitro Study on Green Propolis as a Potential Ingredient of Oral Health Care Products.
Antibiotics (Basel);2022Dec06; 11 (12) . doi:10.3390/antibiotics11121764
2022
Abstract PubMed
Jin YP, Nevarez-Mejia J, Terry AQ, Sosa RA, Heidt S, Valenzuela NM, Rozengurt E, Reed EF,:
Cross-Talk between HLA Class I and TLR4 Mediates P-Selectin Surface Expression and Monocyte Capture to Human Endothelial Cells.
J Immunol;2022Oct01; 209 (7) 1359-1369. doi:10.4049/jimmunol.2200284
2022
Abstract PubMed
Zhang J, Wang Y, Yin C, Gong P, Zhang Z, Zhao L, Waxman S, Jing Y,:
Artesunate improves venetoclax plus cytarabine AML cell targeting by regulating the Noxa/Bim/Mcl-1/p-Chk1 axis.
Cell Death Dis;2022Apr20; 13 (4) 379. doi:10.1038/s41419-022-04810-z
2022
Abstract PubMed
Tang X, Teder T, Samuelsson B, Haeggström JZ,:
The IRE1alpha Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes.
Front Pharmacol;2022; 13 806240. doi:10.3389/fphar.2022.806240
2022
Abstract PubMed
Paasch D, Meyer J, Stamopoulou A, Lenz D, Kuehle J, Kloos D, Buchegger T, Holzinger A, Falk CS, Kloth C, von Kaisenberg CS, Abken H, Schambach A, Lachmann N, Morgan M, Moritz T,:
Ex Vivo Generation of CAR Macrophages from Hematopoietic Stem and Progenitor Cells for Use in Cancer Therapy.
Cells . 2022 Mar 15;11(6):994. . doi:10.3390/cells11060994
2022
Abstract PubMed
Montaño DE, Hartung S, Wich M, Ali R, Jungnickel B, von Lilienfeld-Toal M, Voigt K,:
The TLR-NF-kB axis contributes to the monocytic inflammatory response against a virulent strain of Lichtheimia corymbifera, a causative agent of invasive mucormycosis.
Front Immunol;2022; 13 882921. doi:10.3389/fimmu.2022.882921
2022
Abstract PubMed
Huang S, Lu B, Zhu M, Liu M, Sun Z, Pan X, Wei M,:
Long non-coding RNA LOC644135 is a potential prognostic indicator in cytogenetically normal acute myeloid leukemia.
Expert Rev Hematol;2022 15(7):657-665 doi:10.1080/17474086.2022.2091542
2022
Abstract PubMed
Gerritsen M, Hilgendorf S, Yi G, Wierenga ATJ, Schuringa JJ, Martens JHA, Vellenga E,:
Presence of mutant p53 increases stem-cell frequency and is associated with reduced binding to classical TP53 binding sites in cell lines and primary AMLs.
Exp Hematol;2022 110:39-46 doi:10.1016/j.exphem.2022.03.007
2022
Abstract PubMed
Bollmann LM, Skerhut AJ, Asfaha Y, Horstick N, Hanenberg H, Hamacher A, Kurz T, Kassack MU,:
The Novel Class IIa Selective Histone Deacetylase Inhibitor YAK540 Is Synergistic with Bortezomib in Leukemia Cell Lines.
Int J Mol Sci;2022Nov02; 23 (21) . doi:10.3390/ijms232113398
2022
Abstract PubMed
Liu Z, Duan Z, Zhang D, Xiao P, Zhang T, Xu H, Wang CH, Rao GW, Gan J, Huang Y, Yang CG, Dong Z,:
Structure-Activity Relationships and Antileukemia Effects of the Tricyclic Benzoic Acid FTO Inhibitors.
J Med Chem;2022 Aug 11;65(15):10638-10654. doi:10.1021/acs.jmedchem.2c00848
2022
Abstract PubMed
Brandhofer M, Hoffmann A, Blanchet X, Siminkovitch E, Rohlfing AK, El Bounkari O, Nestele JA, Bild A, Kontos C, Hille K, Rohde V, Fröhlich A, Golemi J, Gokce O, Krammer C, Scheiermann P, Tsilimparis N, Sachs N, Kempf WE, Maegdefessel L, Otabil MK, Megens :
Heterocomplexes between the atypical chemokine MIF and the CXC-motif chemokine CXCL4L1 regulate inflammation and thrombus formation.
Cell Mol Life Sci;2022Sep12; 79 (10) 512. doi:10.1007/s00018-022-04539-0
2022
Abstract PubMed
Stähli A, Scherler C, Zappalà G, Sculean A, Eick S,:
In vitro activity of anti-rheumatic drugs on release of pro-inflammatory cytokines from oral cells in interaction with microorganisms.
Front Oral Health;2022; 3 960732. doi:10.3389/froh.2022.960732
2022
Abstract PubMed
Trad R, Warda W, Alcazer V, Neto da Rocha M, Berceanu A, Nicod C, Haderbache R, Roussel X, Desbrosses Y, Daguindau E, Renosi F, Roumier C, Bouquet L, Biichle S, Guiot M, Seffar E, Caillot D, Depil S, Robinet E, Salma Y, Deconinck E, Deschamps M, Ferrand C:
Chimeric antigen receptor T-cells targeting IL-1RAP: a promising new cellular immunotherapy to treat acute myeloid leukemia.
J Immunother Cancer;2022Jul; 10 (7) . doi:10.1136/jitc-2021-004222
2022
Abstract PubMed
Piszczek P, Wójcik-Piotrowicz K, Guzdek P, Gil K, Kaszuba-Zwoińska J,:
Protein expression changes during phagocytosis influenced by low-frequency electromagnetic field exposure.
Int J Biol Macromol;2022Jul13; 217 481-491. doi:10.1016/j.ijbiomac.2022.07.080
2022
Abstract PubMed
Matissek SJ, Karbalivand M, Han W, Boutilier A, Yzar-Garcia E, Kehoe LL, Gardner DS, Hage A, Fleck K, Jeffers V, Rajsbaum R, Elsawa SF,:
A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling.
Oncotarget;2022; 13 944-959. doi:10.18632/oncotarget.28261
2022
Abstract PubMed
Borbála Horváth L, Krátký M, Pflégr V, László Méhes E, Gyulai G, Kohut G, Babiczky Á, Biri-Kovács B, Éva Baranyai Z, Vinšová J, Erika Bősze S,:
Host cell targeting of novel antimycobacterial 4-aminosalicylic acid derivatives with tuftsin carrier peptides.
Eur J Pharm Biopharm;2022Apr01. doi:10.1016/j.ejpb.2022.03.009
2022
Abstract PubMed
Hein T, Krammer PH, Weyd H,:
Molecular analysis of Annexin expression in cancer.
BMC Cancer;2022Sep19; 22 (1) 994. doi:10.1186/s12885-022-10075-8
2022
Abstract PubMed
Borbála Horváth L, Krátký M, Pflégr V, László Méhes E, Gyulai G, Kohut G, Babiczky Á, Biri-Kovács B, Éva Baranyai Z, Vinšová J, Erika Bősze S,:
Host cell targeting of novel antimycobacterial 4-aminosalicylic acid derivatives with tuftsin carrier peptides.
Eur J Pharm Biopharm;2022Apr01. doi:10.1016/j.ejpb.2022.03.009
2022
Abstract PubMed
Cantini N, Schepetkin IA, Danilenko NV, Khlebnikov AI, Crocetti L, Giovannoni MP, Kirpotina LN, Quinn MT,:
Pyridazinones and Structurally Related Derivatives with Anti-Inflammatory Activity.
Molecules;2022Jun10; 27 (12) . doi:10.3390/molecules27123749
2022
Abstract PubMed
Harelimana JD, Ahor HS, Benner B, Hellmuth S, Adankwah E, Minadzi D, Aniagyei W, Lamptey MNK, Arthur J, Yeboah A, Abass MK, Debrah LB, Owusu DO, Mayatepek E, Seyfarth J, Phillips RO, Jacobsen M,:
Cytokine-induced transient monocyte IL-7Ra expression and the serum milieu in tuberculosis.
Eur J Immunol;2022Mar13. doi:10.1002/eji.202149661
2022
Abstract PubMed
Akula S, Lara S, Olsson AK, Hellman L,:
Quantitative Analysis of the Transcriptome of Two Commonly Used Human Monocytic Cell Lines-THP-1 and Mono Mac 6-Reveals Their Arrest during Early Monocyte/Neutrophil Differentiation.
Int J Mol Sci;2022May22; 23 (10) . doi:10.3390/ijms23105818
2022
Abstract PubMed
Baranyai Z, Biri-Kovács B, Krátký M, Szeder B, Debreczeni ML, Budai J, Kovács B, Horváth L, Pári E, Németh Z, Cervenak L, Zsila F, Méhes E, Kiss É, Vinšová J, Bősze S,:
Cellular Internalization and Inhibition Capacity of New Anti-Glioma Peptide Conjugates: Physicochemical Characterization and Evaluation on Various Monolayer- and 3D-Spheroid-Based in Vitro Platforms.
J Med Chem;20210325; 64 (6) 2982-3005. doi:10.1021/acs.jmedchem.0c01399
2021
Abstract PubMed
Galiègue-Zouitina S, Fu Q, Carton-Latreche C, Poret N, Cheok M, Leprêtre F, Figeac M, Quesnel B, El Bouazzati H, Shelley CS,:
Bimodal expression of RHOH during myelomonocytic differentiation: Implications for the expansion of AML differentiation therapy.
EJHaem;2021May; 2 (2) 196-210. doi:10.1002/jha2.128
2021
Abstract PubMed
Rohr M, Kiefer AM, Kauhl U, Groß J, Opatz T, Erkel G,:
Anti-inflammatory dihydroxanthones from a Diaporthe species.
Biol Chem;2021Aug02. 403(1):89-101 doi:10.1515/hsz-2021-0192
2021
Abstract PubMed
Eisenwort G, Sadovnik I, Keller A, Ivanov D, Peter B, Berger D, Stefanzl G, Bauer K, Slavnitsch K, Greiner G, Gleixner KV, Sperr WR, Willmann M, Sill H, Bettelheim P, Geissler K, Deininger M, Rülicke T, Valent P,:
Phenotypic characterization of leukemia-initiating stem cells in chronic myelomonocytic leukemia.
Leukemia; 2021 Mar 30 . doi:10.1038/s41375-021-01227-z
2021
Abstract PubMed
Horváti K, Fodor K, Pályi B, Henczkó J, Balka G, Gyulai G, Kiss É, Biri-Kovács B, Senoner Z, Bősze S.:
Novel Assay Platform to Evaluate Intracellular Killing of Mycobacterium tuberculosis: In Vitro and In Vivo Validation.
Front Immunol. 2021 Nov 12;12:750496
2021
Abstract PubMed
Warda W, Da Rocha MN, Trad R, Haderbache R, Salma Y, Bouquet L, Roussel X, Nicod C, Deschamps M, Ferrand C,:
Overcoming target epitope masking resistance that can occur on low-antigen-expresser AML blasts after IL-1RAP chimeric antigen receptor T cell therapy using the inducible caspase 9 suicide gene safety switch.
Cancer Gene Ther; 2021 Jan 07 . doi:10.1038/s41417-020-00284-3
2021
Abstract PubMed
Sebák F, Horváth LB, Kovács D, Szolomájer J, Tóth GK, Babiczky Á, Bősze S, Bodor A,:
Novel Lysine-Rich Delivery Peptides of Plant Origin ERD and Human S100: The Effect of Carboxyfluorescein Conjugation, Influence of Aromatic and Proline Residues, Cellular Internalization, and Penetration Ability.
ACS Omega;2021Dec21; 6 (50) 34470-34484. doi:10.1021/acsomega.1c04637
2021
Abstract PubMed
Schenz J, Heilig L, Lohse T, Tichy L, Bomans K, Büttner M, Weigand MA, Uhle F,:
Extracellular Lactate Acts as a Metabolic Checkpoint and Shapes Monocyte Function Time Dependently.
Front Immunol;2021; 12 729209. doi:10.3389/fimmu.2021.729209
2021
Abstract PubMed
Prins MMC, van Roest M, Vermeulen JLM, Tjabringa GS, van de Graaf SFJ, Koelink PJ, Wildenberg ME,:
Applicability of different cell line-derived dendritic cell-like cells in autophagy research.
J Immunol Methods;2021Jul26 113106. doi:10.1016/j.jim.2021.113106
2021
Abstract PubMed
Linzenbold W, Fech A, Hofmann M, Aicher WK, Enderle MD,:
Novel Techniques to Improve Precise Cell Injection.
Int J Mol Sci;2021Jun14; 22 (12) . doi:10.3390/ijms22126367
2021
Abstract PubMed
Haderbache R, Warda W, Hervouet E, da Rocha MN, Trad R, Allain V, Nicod C, Thieblemeont C, Boissel N, Varlet P, Agha IY, Bouquet L, Guiot M, Venet F, Sujobert P, Roussel X, Rouzaire PO, Caillot D, Casasnovas O, Bories JC, Bachy E, Caillat-Zucman S, Descha:
Droplet digital PCR allows vector copy number assessment and monitoring of experimental CAR T cells in murine xenograft models or approved CD19 CAR T cell-treated patients.
J Transl Med; 2021 Jun 21 ; 19 (1) 265. doi:10.1186/s12967-021-02925-z
2021
Abstract PubMed
Dickhout A, Kaczor DM, Heinzmann ACA, Brouns SLN, Heemskerk JWM, van Zandvoort MAMJ, Koenen RR,:
Rapid Internalization and Nuclear Translocation of CCL5 and CXCL4 in Endothelial Cells.
Int J Mol Sci;2021Jul08; 22 (14) . doi:10.3390/ijms22147332
2021
Abstract PubMed
Veerman RE, Teeuwen L, Czarnewski P, Güclüler Akpinar G, Sandberg A, Cao X, Pernemalm M, Orre LM, Gabrielsson S, Eldh M,:
Molecular evaluation of five different isolation methods for extracellular vesicles reveals different clinical applicability and subcellular origin.
J Extracell Vesicles;2021Jul; 10 (9) 12128. doi:10.1002/jev2.12128
2021
Abstract PubMed
Lara S, Anania JC, Virtanen A, Stenhammar V, Kleinau S,:
Importance of antibody isotypes in anti-tumor immunity by monocytes and complement using human-immune tumor models.
Eur J Immunol; 2021 May;51(5):1218-1233. doi:10.1002/eji.202048885
2021
Abstract PubMed
Lewis AH, Bridges CS, Punia VS, Cooper AFJ, Puppi M, Lacorazza HD,:
Kruppel-like factor 4 promotes survival and expansion in acute myeloid leukemia cells.
Oncotarget; 2021 Feb 16 ; 12 (4) 255-267. doi:10.18632/oncotarget.27878
2021
Abstract PubMed
Åbacka H, Hansen JS, Huang P, Venskutonytė R, Hyrenius-Wittsten A, Poli G, Tuccinardi T, Granchi C, Minutolo F, Hagström-Andersson AK, Lindkvist-Petersson K,:
Targeting GLUT1 in acute myeloid leukemia to overcome cytarabine resistance.
Haematologica; 2021 Apr 1;106(4):1163-1166. doi: 10.3324/haematol.2020.246843.
2021
Abstract PubMed
Antonelli A, Scarpa ES, Magnani M,:
Human Red Blood Cells Modulate Cytokine Expression in Monocytes/Macrophages Under Anoxic Conditions.
Front Physiol; 2021 ; 12 632682. doi:10.3389/fphys.2021.632682
2021
Abstract PubMed
Hassan MIA, Keller M, Hillger M, Binder U, Reuter S, Herold K, Telagathoti A, Dahse HM, Wicht S, Trinks N, Nietzsche S, Deckert-Gaudig T, Deckert V, Mrowka R, Terpitz U, Peter Saluz H, Voigt K,:
The impact of episporic modification of Lichtheimia corymbifera on virulence and interaction with phagocytes.
Comput Struct Biotechnol J; 2021 ; 19 880-896. doi:10.1016/j.csbj.2021.01.023
2021
Abstract PubMed
Kósa N, Zolcsák Á, Voszka I, Csík G, Horváti K, Horváth L, Bősze S, Herenyi L,:
Comparison of the Efficacy of Two Novel Antitubercular Agents in Free and Liposome-Encapsulated Formulations.
Int J Mol Sci; 2021 Feb 28 ; 22 (5) . doi:10.3390/ijms22052457
2021
Abstract PubMed
Quemé-Peña M, Ricci M, Juhász T, Horváti K, Bősze S, Biri-Kovács B, Szeder B, Zsila F, Beke-Somfai T,:
Old Polyanionic Drug Suramin Suppresses Detrimental Cytotoxicity of the Host Defense Peptide LL-37.
ACS Pharmacol Transl Sci; 2021 Feb 12 ; 4 (1) 155-167. doi:10.1021/acsptsci.0c00155
2021
Abstract PubMed
Uebbing S, Kreiß M, Scholl F, Häfner AK, Sürün D, Garscha U, Werz O, Basavarajappa D, Samuelsson B, Rådmark O, Suess B, Steinhilber D.:
Modulation of microRNA processing by 5-lipoxygenase
FASEB J. 2021 Feb;35(2):e21193.
2021
Abstract PubMed
Radakovic S, Andreoli N, Schmid S, Nietzsche S, Zumbrunn J, Sculean A, Eick S,:
Taurolidine Acts on Bacterial Virulence Factors and Does Not Induce Resistance in Periodontitis-Associated Bacteria-An In-Vitro Study.
Antibiotics (Basel);2020Apr07; 9 (4) .:166 doi:10.3390/antibiotics9040166
2020
Abstract PubMed
Gorby C, Sotolongo Bellón J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, Moraga I,:
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses.
Sci Signal;20200915; 13 (649) . doi:10.1126/scisignal.abc0653
2020
Abstract PubMed
Lenard A, Xie HM, Pastuer T, Shank T, Libbrecht C, Kingsley M, Riedel SS, Yuan ZF, Zhu N, Neff T, Bernt KM,:
Epigenetic regulation of protein translation in KMT2A-rearranged AML.
Exp Hematol;202005; 85 57-69. doi:10.1016/j.exphem.2020.04.007
2020
Abstract PubMed
Kontos C, El Bounkari O, Krammer C, Sinitski D, Hille K, Zan C, Yan G, Wang S, Gao Y, Brandhofer M, Megens RTA, Hoffmann A, Pauli J, Asare Y, Gerra S, Bourilhon P, Leng L, Eckstein HH, Kempf WE, Pelisek J, Gokce O, Maegdefessel L, Bucala R, Dichgans M, We:
Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
Nat Commun; 2020 11 25 ; 11 (1) 5981. doi:10.1038/s41467-020-19764-z
2020
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Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6669-E6678
2016
Abstract PubMed
de Vallière C, Cosin-Roger J, Simmen S, Atrott K, Melhem H, Zeitz J, Madanchi M, Tcymbarevich I, Fried M, Kullak-Ublick GA, Vavricka SR, Misselwitz B, Seuwen K, Wagner CA, Eloranta JJ, Rogler G, Ruiz PA.:
Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein-Coupled Receptor OGR1 (GPR68).
Cell Mol Gastroenterol Hepatol. 2016 Jun 25;2(6):796-810
2016
Abstract PubMed
Kosciuczuk EM, Saleiro D, Kroczynska B, Beauchamp EM, Eckerdt F, Blyth GT, Abedin SM, Giles FJ, Altman JK, Platanias LC.:
Merestinib blocks Mnk kinase activity in acute myeloid leukemia progenitors and exhibits antileukemic effects in vitro and in vivo.
Blood. 2016 Jul 21;128(3):410-4
2016
Abstract PubMed
Gonnissen D, Qu Y, Langer K, Öztürk C, Zhao Y, Chen C, Seebohm G, Düfer M, Fuchs H, Galla HJ, Riehemann K.:
Comparison of cellular effects of starch-coated SPIONs and poly(lactic-co-glycolic acid) matrix nanoparticles on human monocytes.
Int J Nanomedicine. 2016 Oct 14;11:5221-5236.
2016
Abstract PubMed
Ábrahám Á, Baranyai Z, Gyulai G, Pári E, Horváti K, Bősze S, Kiss É.:
Comparative analysis of new peptide conjugates of antitubercular drug candidates-Model membrane and in vitro studies.
Colloids Surf B Biointerfaces. 2016 Nov 1;147:106-15
2016
Abstract PubMed
Zhang L, Stuber F, Lippuner C, Schiff M, Stamer UM.:
Phorbol-12-myristate-13-acetate induces nociceptin in human Mono Mac 6 cells via multiple transduction signalling pathways.
Br J Anaesth. 2016 Aug;117(2):250-7
2016
Abstract PubMed
Zariri A, Beskers J, van de Waterbeemd B, Hamstra HJ, Bindels TH, van Riet E, van Putten JP, van der Ley P.:
Meningococcal Outer Membrane Vesicle Composition-Dependent Activation of the Innate Immune Response.
Infect Immun. 2016 Sep 19;84(10):3024-33
2016
Abstract PubMed
Witola WH, Matthews K, McHugh M.:
In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus.
Int J Parasitol Drugs Drug Resist. 2016 Jan 18;6(1):44-53
2016
Abstract PubMed
Mohebbi S, Erfurth F, Hennersdorf P, Brakhage AA, Saluz HP.:
Hyperspectral Imaging Using Intracellular Spies: Quantitative Real-Time Measurement of Intracellular Parameters In Vivo during Interaction of the Pathogenic Fungus Aspergillus fumigatus with Human Monocytes.
PLoS One. 2016 Oct 11;11(10):e0163505
2016
Abstract PubMed
Ebner P, Rinker J, Nguyen MT, Popella P, Nega M, Luqman A, Schittek B, Di Marco M, Stevanovic S, Götz F.:
Excreted Cytoplasmic Proteins Contribute to Pathogenicity in Staphylococcus aureus.
Infect Immun. 2016 May 24;84(6):1672-81
2016
Abstract PubMed
Krejbich-Trotot P, Belarbi E, Ralambondrainy M, El-Kalamouni C, Viranaicken W, Roques P, Desprès P, Gadea G.:
The growth of arthralgic Ross River virus is restricted in human monocytic cells.
Virus Res. 2016 Sep 13;225:64-68
2016
Abstract PubMed
Lukic A, Ji J, Idborg H, Samuelsson B, Palmberg L, Gabrielsson S, Rådmark O.:
Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.
J Lipid Res. 2016 Sep;57(9):1659-69
2016
Abstract PubMed
Riemann A, Wußling H, Loppnow H, Fu H, Reime S, Thews O.:
Acidosis differently modulates the inflammatory program in monocytes and macrophages.
Biochim Biophys Acta. 2016 Jan;1862(1):72-81
2016
Abstract PubMed
Saul MJ, Stein S, Grez M, Jakobsson PJ, Steinhilber D, Suess B.:
UPF1 regulates myeloid cell functions and S100A9 expression by the hnRNP E2/miRNA-328 balance.
Sci Rep. 2016 Aug 30;6:31995
2016
Abstract PubMed
Vordenbäumen S, Saenger T, Braukmann A, Tahan T, Bleck E, Jose J, Schneider M.:
Human casein alpha s1 induces proinflammatory cytokine expression in monocytic cells by TLR4 signaling.
Mol Nutr Food Res. 2016 May;60(5):1079-89
2016
Abstract PubMed
Xiong Y, Murphy M, Manavalan TT, Pattabiraman G, Qiu F, Chang HH, Ho IC, Medvedev AE.:
Endotoxin Tolerance Inhibits Lyn and c-Src Phosphorylation and Association with Toll-Like Receptor 4 but Increases Expression and Activity of Protein Phosphatases.
J Innate Immun. 2016;8(2):171-84.
2016
Abstract PubMed
Hoonakker ME, Verhagen LM, Pupo E, de Haan A, Metz B, Hendriksen CF, Han WG, Sloots A.:
Vaccine-Mediated Activation of Human TLR4 Is Affected by Modulation of Culture Conditions during Whole-Cell Pertussis Vaccine Preparation.
PLoS One. 2016 Aug 22;11(8):e0161428
2016
Abstract PubMed
Poussin C, Laurent A, Peitsch MC, Hoeng J, De Leon H.:
Systems toxicology-based assessment of the candidate modified risk tobacco product THS2.2 for the adhesion of monocytic cells to human coronary arterial endothelial cells.
Toxicology.;339:73-86
2016
Abstract PubMed
Su S, Zhao Q, He C, Huang D, Liu J, Chen F, Chen J, Liao JY, Cui X, Zeng Y, Yao H, Su F, Liu Q, Jiang S, Song E.:
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.
Nat Commun. 2015 Oct 5;6:8523.
2015
Abstract PubMed
Chen CW, Koche RP, Sinha AU, Deshpande AJ, Zhu N, Eng R, Doench JG, Xu H, Chu SH, Qi J, Wang X, Delaney C, Bernt KM, Root DE, Hahn WC, Bradner JE, Armstrong SA.:
DOT1L inhibits SIRT1-mediated epigenetic silencing to maintain leukemic gene expression in MLL-rearranged leukemia.
Nat Med. 2015 Apr;21(4):335-43
2015
Abstract PubMed
Murphy MB, Xiong Y, Pattabiraman G, Manavalan TT, Qiu F, Medvedev AE.:
Pellino-3 promotes endotoxin tolerance and acts as a negative regulator of TLR2 and TLR4 signaling.
J Leukoc Biol. 2015 Dec;98(6):963-74
2015
Abstract PubMed
Charron CS, Dawson HD, Albaugh GP, Solverson PM, Vinyard BT, Solano-Aguilar GI, Molokin A, Novotny JA.:
A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans.
J Nutr. 145:2448-55
2015
Abstract PubMed
Lehmann C, Homann J, Ball AK, Blöcher R, Kleinschmidt TK, Basavarajappa D, Angioni C, Ferreirós N, Häfner AK, Rådmark O, Proschak E, Haeggström JZ, Geisslinger G, Parnham MJ, Steinhilber D, Kahnt AS.:
Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein.
FASEB J.;29:5029-43.
2015
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Huber R, Panterodt T, Welz B, Christmann M, Friesenhagen J, Westphal A, Pietsch D, Brand K.:
C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation.
PLoS One;10:e0144338
2015
Abstract PubMed
Poussin C, Laurent A, Peitsch MC, Hoeng J, De Leon H.:
Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte-Endothelial Cell Adhesion.
Toxicol Sci. 147:370-85
2015
Abstract PubMed
Żołnierczyk AK, Mączka WK, Grabarczyk M, Wińska K, Woźniak E, Anioł M.:
Isoxanthohumol--Biologically active hop flavonoid.
Fitoterapia.;103:71-82.
2015
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Kleinschmidt TK, Haraldsson M, Basavarajappa D, Lundeberg E, Thulasingam M, Ekoff M, Fauland A, Lehmann C, Kahnt AS, Lindbom L, Haeggström JZ.:
Tandem Benzophenone Amino Pyridines, Potent and Selective Inhibitors of Human Leukotriene C4 Synthase.
J Pharmacol Exp Ther. ;355:108-16
2015
Abstract PubMed
Kawata K, Iwai A, Muramatsu D, Aoki S, Uchiyama H, Okabe M, Hayakawa S, Takaoka A, Miyazaki T.:
Stimulation of macrophages with the β-glucan produced by aureobasidium pullulans promotes the secretion of tumor necrosis factor-related apoptosis inducing ligand (TRAIL).
PLoS One.;10:e0124809.
2015
Abstract PubMed
de Vallière C, Wang Y, Eloranta JJ, Vidal S, Clay I, Spalinger MR, Tcymbarevich I, Terhalle A, Ludwig MG, Suply T, Fried M, Kullak-Ublick GA, Frey-Wagner I, Scharl M, Seuwen K, Wagner CA, Rogler G:
2. G Protein-coupled pH-sensing Receptor OGR1 Is a Regulator of Intestinal Inflammation.
Inflamm Bowel Dis.;21:1269-81
2015
Abstract PubMed
Baranyai Z, Krátký M, Vinšová J, Szabó N, Senoner Z, Horváti K, Stolaříková J, Dávid S, Bősze S.:
Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates.
Eur J Med Chem.;101:692-704
2015
Abstract PubMed
Murphy M, Xiong Y, Pattabiraman G, Qiu F, Medvedev AE.:
Pellino-1 Positively Regulates Toll-like Receptor (TLR) 2 and TLR4 Signaling and Is Suppressed upon Induction of Endotoxin Tolerance.
J Biol Chem.;290:19218-32
2015
Abstract PubMed
Nguyen MT, Kraft B, Yu W, Demicrioglu DD, Hertlein T, Burian M, Schmaler M, Boller K, Bekeredjian-Ding I, Ohlsen K, Schittek B, Götz F.:
The νSaα Specific Lipoprotein Like Cluster (lpl) of S. aureus USA300 Contributes to Immune Stimulation and Invasion in Human Cells.
PLoS Pathog.;11:e1004984
2015
Abstract PubMed
Valenzuela NM, Trinh KR, Mulder A, Morrison SL, Reed EF.:
Monocyte recruitment by HLA IgG-activated endothelium: the relationship between IgG subclass and FcγRIIa polymorphisms.
Am J Transplant. ;15:1502-18
2015
Abstract PubMed
Hoonakker ME, Verhagen LM, Hendriksen CF, van Els CA, Vandebriel RJ, Sloots A, Han WG.:
In vitro innate immune cell based models to assess whole cell Bordetella pertussis vaccine quality: a proof of principle.
Biologicals.;43:100-9
2015
Abstract PubMed
Knape T, Flesch D, Kuchler L, Sha LK, Giegerich AK, Labocha S, Ferreirós N, Schmid T, Wurglics M, Schubert-Zsilavecz M, Proschak E, Brüne B, Parnham MJ, von Knethen A.:
Identification and characterisation of a prototype for a new class of competitive PPARγ antagonists.
Eur J Pharmacol.;755:16-26.
2015
Abstract PubMed
Haile LA, Puig M, Kelley-Baker L, Verthelyi D.:
Detection of innate immune response modulating impurities in therapeutic proteins.
PLoS One.;10:e0125078
2015
Abstract PubMed
Busch S, Auth E, Scholl F, Huenecke S, Koehl U, Suess B, Steinhilber D.:
5-lipoxygenase is a direct target of miR-19a-3p and miR-125b-5p.
J Immunol;194:1646-53
2015
Abstract PubMed
Brummelman J, Veerman RE, Hamstra HJ, Deuss AJ, Schuijt TJ, Sloots A, Kuipers B, van Els CA, van der Ley P, Mooi FR, Han WG, Pinelli E.:
Bordetella pertussis Naturally Occurring Isolates with Altered Lipooligosaccharide Structure Fail To Fully Mature Human Dendritic Cells.
Infect Immun.;83(1):227-38
2015
Abstract PubMed
Kim HS, Lim GY, Hwang J, Ryoo ZY, Huh TL, Lee S.:
Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia.
Int J Mol Med.;34:1675-80
2014
Abstract PubMed
É. Kiss, G. Gyulai, Cs. B. Pénzes, M. Idei, K. Horváti, B. Bacsa, Sz. Bősze:
Tuneable surface modification of PLGA nanoparticles carrying new antitubercular drug candidate
Colloids and Surfaces A: Physicochemical and Engineering Aspects 458: 178
2014
Abstract PubMed
Horváti K, Bacsa B, Kiss E, Gyulai G, Fodor K, Balka G, Rusvai M, Szabó E, Hudecz F, Bősze S.:
Nanoparticle encapsulated lipopeptide conjugate of antitubercular drug isoniazid: in vitro intracellular activity and in vivo efficacy in a Guinea pig model of tuberculosis.
Bioconjug Chem.;25:2260-8
2014
Abstract PubMed
Kim HS, Lim GY, Hwang J, Ryoo ZY, Huh TL, Lee S.:
Induction of apoptosis by obovatol as a novel therapeutic strategy for acute myeloid leukemia.
nt J Mol Med.;34:1675-80
2014
Abstract PubMed
Quang Trong Le, Sahar Lotfi-Emran, Hae-Ki Min, Lawrence B. Schwartz:
A Simple, Sensitive and Safe Method to Determine the Human α/β-Tryptase Genotype
PLoS One.; 9: e114944.
2014
Abstract PubMed
Lowe HI, Toyang NJ, Watson CT, Ayeah KN, Bryant J.:
Antileukemic activity of Tillandsia recurvata and some of its cycloartanes.
Anticancer Res.;34:3505-9.
2014
Abstract PubMed
Pierzchalski P1, Jastrzebska M, Link-Lenczowski P, Leja-Szpak A, Bonior J, Jaworek J, Okon K, Wojcik P.:
The dynamics of heat shock system activation in Monomac-6 cells upon Helicobacter pylori infection.
J Physiol Pharmacol.;65(6):791-800.
2014
Abstract PubMed
Ahmad K, Katryniok C, Scholz B, Merkens J, Löscher D, Marschalek R, Steinhilber D.:
Inhibition of class I HDACs abrogates the dominant effect of MLL-AF4 by activation of wild-type MLL.
Oncogenesis.;3:e127
2014
Abstract PubMed
Wen B, Combes V, Bonhoure A, Weksler BB, Couraud PO, Grau GE.:
Endotoxin-induced monocytic microparticles have contrasting effects on endothelial inflammatory responses.
PLoS One.;9:e91597
2014
Abstract PubMed
Bollmann F, Art J, Henke J, Schrick K, Besche V, Bros M, Li H, Siuda D, Handler N, Bauer F, Erker T, Behnke F, Mönch B, Härdle L, Hoffmann M, Chen CY, Förstermann U, Dirsch VM, Werz O, Kleinert H, Pautz A.:
Resveratrol post-transcriptionally regulates pro-inflammatory gene expression via regulation of KSRP RNA binding activity.
Nucleic Acids Res.;42:12555-69
2014
Abstract PubMed
Bohnert M, Scherer O, Wiechmann K, König S, Dahse HM, Hoffmeister D, Werz O.:
Melleolides induce rapid cell death in human primary monocytes and cancer cells.
Bioorg Med Chem. ;22:3856-61
2014
Abstract PubMed
Vijayan S, Asare Y, Grommes J, Soehnlein O, Lutgens E, Shagdarsuren G, Togtokh A, Jacobs MJ, Fischer JW, Bernhagen J, Weber C, Schober A, Shagdarsuren E.:
High expression of C5L2 correlates with high proinflammatory cytokine expression in advanced human atherosclerotic plaques.
Am J Pathol.;184:2123-33
2014
Abstract PubMed
Lawrence H, Deehan D, Holland J, Kirby J, Tyson-Capper A.:
The immunobiology of cobalt: demonstration of a potential aetiology for inflammatory pseudotumours after metal-on-metal replacement of the hip.
Bone Joint J. ;96-B :1172-7
2014
Abstract PubMed
Schäffler H, Demircioglu DD, Kühner D, Menz S, Bender A, Autenrieth IB, Bodammer P, Lamprecht G, Götz F, Frick JS.:
Receptor 2 Costimulation with Lipoproteins in Dendritic Cells.
Infect Immun.;82(11):4681-8.
2014
Abstract PubMed
Willi M, Belibasakis GN, Bostanci N.:
Expression and regulation of triggering receptor expressed on myeloid cells 1 in periodontal diseases.
Clin Exp Immunol.;178:190-200
2014
Abstract PubMed
Basavarajappa D, Wan M, Lukic A, Steinhilber D, Samuelsson B, Rådmark O.:
Roles of coactosin-like protein (CLP) and 5-lipoxygenase-activating protein (FLAP) in cellular leukotriene biosynthesis.
Proc Natl Acad Sci U S A. ;111:11371-6
2014
Abstract PubMed
Friedrichs B, Neumann U, Schüller J, Peck MJ.:
Cigarette-smoke-induced priming of neutrophils from smokers and non-smokers for increased oxidative burst response is mediated by TNF-α.
Toxicol In Vitro.;28:1249-58
2014
Abstract PubMed
Pergola C, Gerstmeier J, Mönch B, Çalışkan B, Luderer S, Weinigel C, Barz D, Maczewsky J, Pace S, Rossi A, Sautebin L, Banoglu E, Werz O.:
The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP)
Br J Pharmacol.;171:3051-64.
2014
Abstract PubMed
Witola WH, Liu SR, Montpetit A, Welti R, Hypolite M, Roth M, Zhou Y, Mui E, Cesbron-Delauw MF, Fournie GJ, Cavailles P, Bisanz C, Boyer K, Withers S, Noble AG, Swisher CN, Heydemann PT, Rabiah P, Muench SP, McLeod R.:
ALOX12 in Human Toxoplasmosis
Infect Immun.;82:2670-2679
2014
Abstract PubMed
Markoutsa S, Sürün D, Karas M, Hofmann B, Steinhilber D, Sorg BL.:
Analysis of 5-lipoxygenase phosphorylation on molecular level by MALDI-MS.
FEBS J. ;281:1931-47.
2014
Abstract PubMed
de Leeuw DC, Denkers F, Olthof MC, Rutten AP, Pouwels W, Jan Schuurhuis G, Ossenkoppele GJ, Smit L:
Attenuation of microRNA-126 expression that drives CD34+38- stem/progenitor cells in acute myeloid leukemia leads to tumor eradication.
Cancer Res.;74:2094-105.
2014
Abstract PubMed
Poussin C, Gallitz I, Schlage WK, Steffen Y, Stolle K, Lebrun S, Hoeng J, Peitsch MC, Lietz M.:
Mechanism of an indirect effect of aqueous cigarette smoke extract on the adhesion of monocytic cells to endothelial cells in an in vitro assay revealed by transcriptomics analysis.
Toxicol In Vitro.;28:896-908
2014
Abstract PubMed
Turapov O, Waddell SJ, Burke B, Glenn S, Sarybaeva AA, Tudo G, Labesse G, Young DI, Young M, Andrew PW, Butcher PD, Cohen-Gonsaud M, Mukamolova GV:
Antimicrobial treatment improves mycobacterial survival in nonpermissive growth conditions.
Antimicrob Agents Chemother. 181:174-80
2014
Abstract PubMed
Zughaier SM, Kandler JL, Shafer WM.:
Neisseria gonorrhoeae modulates iron-limiting innate immune defenses in macrophages.
PLoS One;9:e87688
2014
Abstract PubMed
Rye MS, Scaman ES, Thornton RB, Vijayasekaran S, Coates HL, Francis RW, Pennell CE, Blackwell JM, Jamieson SE.:
Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3.
BMC Med Genet.;15:18
2014
Abstract PubMed
Lauer SA, Iyer S, Sanchez T, Forst CV, Bowden B, Carlson K, Sriranganathan N, Boyle SM:
Proteomic Analysis of Detergent Resistant Membrane Domains during Early Interaction of Macrophages with Rough and Smooth Brucella melitensis.
PLoS One ;9:e91706
2014
Abstract PubMed
de Groote ML, Kazemier HG, Huisman C, van der Gun BT, Faas MM, Rots MG.:
Upregulation of endogenous ICAM-1 reduces ovarian cancer cell growth in the absence of immune cells.
Int J Cancer.;134:280-90
2014
Abstract PubMed
Pupo E1, Hamstra HJ, Meiring H, van der Ley P.:
Lipopolysaccharide engineering in Neisseria meningitidis: Structural analysis of different pentaacyl lipid A mutants and comparison of their modified agonist properties.
J Biol Chem.
2014
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Li Z, Zhang Z, Li Y, Arnovitz S, Chen P, Huang H, Jiang X, Hong GM, Kunjamma RB, Ren H, He C, Wang CZ, Elkahloun AG, Valk PJ, Döhner K, Neilly MB, Bullinger L, Delwel R, Löwenberg B, Liu PP, Morgan R, Rowley JD, Yuan CS, Chen J.:
PBX3 is an important cofactor of HOXA9 in leukemogenesis.
Blood. 2013 Feb 21;121(8):1422-31
2013
Abstract PubMed
Mastelic B, Garçon N, Del Giudice G, Golding H, Gruber M, Neels P, Fritzell B.:
Predictive markers of safety and immunogenicity of adjuvanted vaccines.
Biologicals 41:458-68
2013
Abstract PubMed
Kühnemuth B, Mühlberg L, Schipper M, Griesmann H, Neesse A, Milosevic N, Wissniowski T, Buchholz M, Gress TM, Michl P:
CUX1 modulates polarization of tumor-associated macrophages by antagonizing NF-κB signaling.
Oncogene, 1-11
2013
Abstract PubMed
Tuszynski GP, Rothman VL.:
Angiocidin induces differentiation of acute myeloid leukemia cells.
Exp Mol Pathol.;95:249-54
2013
Abstract PubMed
Lee JC1, Espéli M, Anderson CA, Linterman MA, Pocock JM, Williams NJ, Roberts R, Viatte S, Fu B, Peshu N, Hien TT, Phu NH, Wesley E, Edwards C, Ahmad T, Mansfield JC, Gearry R, Dunstan S, Williams TN, Barton A, Vinuesa CG; UK IBD Genetics Consortium, Par:
Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway
Cell.;155:57-69
2013
Abstract PubMed
Paland N1, Aharoni S, Fuhrman B.:
Urokinase-type plasminogen activator (uPA) modulates monocyte-to-macrophage differentiation and prevents Ox-LDL-induced macrophage apoptosis
Atherosclerosis.;231:29-38.
2013
Abstract PubMed
Khare, Naveen K.:
Design, synthesis and activity of thio-linked arabinofuranosyl disaccharides against mycobacterial tuberculosis (MTB) and Mycobacterium avium complex (MAC).
ARKIVOC(ii) 290-315
2013
Abstract PubMed
Valenzuela NM1, Hong L, Shen XD, Gao F, Young SH, Rozengurt E, Kupiec-Weglinski JW, Fishbein MC, Reed EF:
Blockade of p-selectin is sufficient to reduce MHC I antibody-elicited monocyte recruitment in vitro and in vivo
Am J Transplant;13:299-311
2013
Abstract PubMed
Xu J1, Mojsoska B.:
The immunomodulation effect of Aronia extract lacks association with its antioxidant anthocyanins
J Med Food;16:334-42
2013
Abstract PubMed
Timm M, Saaby L, Moesby L, Hansen EW.:
Considerations regarding use of solvents in in vitro cell based assays.
Cytotechnology.;65:887-94
2013
Abstract PubMed
Valenzuela NM, Mulder A, Reed EF:
HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs
J Immunol. ;190(12):6635-50
2013
Abstract PubMed
Miller PG, Al-Shahrour F, Hartwell KA, Chu LP, Järas M, Puram RV, Puissant A, Callahan KP, Ashton J, McConkey ME, Poveromo LP, Cowley GS, Kharas MG, Labelle M, Shterental S, Fujisaki J, Silberstein L, Alexe G, Al-Hajj MA, Shelton CA, Armstrong SA, Root D:
In Vivo RNAi Screening Identifies a Leukemia-Specific Dependence on Integrin Beta 3 Signaling
Cancer Cell. pii: S1535-6108(13)00197-9
2013
Abstract PubMed
Wöbke TK, von Knethen A, Steinhilber D, Sorg BL:
CD69 Is a TGF-β/1α,25-dihydroxyvitamin D3 Target Gene in Monocytes
PLoS One. ;8(5):e64635.
2013
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Raby AC, Holst B, Le Bouder E, Diaz C, Ferran E, Conraux L, Guillemot JC, Coles B, Kift-Morgan A, Colmont CS, Szakmany T, Ferrara P, Hall JE, Topley N, Labeta MO:
Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens
Sci Transl Med. ;5(185):185ra64
2013
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Ochs MJ, Ossipova E, Oliynyk G, Steinhilber D, Suess B, Jakobsson PJ:
Mass spectrometry based proteomics identifies UPF1 as a critical gene expression regulator in Mono Mac 6 cells
J Proteome Res.
2013
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Hinterleitner C, Huelsenbeck J, Henninger C, Wartlick F, Schorr A, Kaina B, Fritz G:
Rac1 signaling protects monocytic AML cells expressing the MLL-AF9 oncogene from caspase-mediated apoptotic death
Apoptosis.
2013
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Ehlers C, Schirmer S, Kehlenbach RH, Hauber J, Chemnitz J:
Post-transcriptional regulation of CD83 expression by AUF1 proteins
Nucleic Acids Res. ;41(1):206-19
2013
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Rye MS, Wiertsema SP, Scaman ES, Thornton R, Francis RW, Vijayasekaran S, Coates HL, Jamieson SE, Blackwell JM:
Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population
Infect Genet Evol. 16:411-8
2013
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Xu J, Mojsoska B:
The immunomodulation effect of aronia extract lacks association with its antioxidant anthocyanins
J Med Food. ;16(4):334-42
2013
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Khare NK, Duarte FJ, Reynolds RC, Maddry JA:
Design, synthesis and activity of thio-linked arabinofuranosyl disaccharides against mycobacterial tuberculosis AND (MTB) AND and Mycobacterium avium complex AND (MAC)
ARKIVOC (ii) 290-315
2013
Abstract PubMed
Manosroi J, Tangjai T, Werner RG, Götz F, Manosroi W, Manosroi A:
Potent and Prolonged Hypoglycemic Activity of an Oral Insulin - Tat Mixture in Diabetic Mice
Drug Res (Stuttg).
2013
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Schepetkin IA, Kouakou K, Yapi A, Kirpotina LN, Jutila MA, Quinn MT:
Immunomodulatory and hemagglutinating activities of acidic polysaccharides isolated from Combretum racemosum
Int Immunopharmacol. ;15(3):628-37
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Lajko E, Szabo I, Andody K, Pungor A, Mezö G, Köhidai L:
Investigation on chemotactic drug targeting (chemotaxis and adhesion) inducer effect of GnRH-III derivatives in Tetrahymena and human leukemia cell line
J Pept Sci. ;19(1):46-58
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Thomas AW, Davies NA, Moir H, Watkeys L, Ruffino JS, Isa SA, Butcher LR, Hughes MG, Morris K, Webb R.:
Exercise-associated generation of PPARγ ligands activates PPARγ signaling events and upregulates genes related to lipid metabolism.
J Appl Physiol ;112:806-15.
2012
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Kunnen A, Dekker DC, van Pampus MG, Harmsen HJ, Aarnoudse JG, Abbas F, Faas MM.:
Cytokine production induced by non-encapsulated and encapsulated Porphyromonas gingivalis strains.
Arch Oral Biol. 57:1558-66
2012
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Kunisch R, Kamal E, Lewin A:
The role of the mycobacterial DNA-binding protein 1 (MDP1) from Mycobacterium bovis BCG in host cell interaction
BMC Microbiol. 3;12:165
2012
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Müller-Schmah C, Solari L, Weis R, Pfeifer D, Scheibenbogen C, Trepel M, May AM, Engelhardt R, Lübbert M:
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Ann Hematol. ;91(1):27-32
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Raval A, Sridhar KJ, Patel S, Turnbull BB, Greenberg PL, Mitchell BS:
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Blood. 6;120(24):4812-8
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Abstract PubMed
Rodenburg GD, Fransen F, Bogaert D, Schipper K, Groenwold RH, Hamstra HJ, Westerhuis BM, van de Beek D, van der Ley P, Sanders EA, van der Ende A:
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Bunuales M, Garcia-Aragoncillo E, Casado R, Quetglas JI, Hervas-Stubbs S, Bortolanza S, Benavides-Vallve C, Ortiz-de-Solorzano C, Prieto J, Hernandez-Alcoceba R:
Evaluation of monocytes as carriers for armed oncolytic adenoviruses in murine and Syrian hamster models of cancer
Hum Gene Ther. ;23(12):1258-68
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Kaszuba-Zwoinska J, Chorobik P, Juszczak K, Zaraska W, Thor PJ:
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Schreiber D, Jung M, Sandjo LP, Liermann JC, Opatz T, Erkel G:
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J Antibiot (Tokyo). ;65(9):473-7
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Kunnen A, Dekker DC, van Pampus MG, Harmsen HJ, Aarnoudse JG, Abbas F, Faas MM:
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Arch Oral Biol. 57: 1558-1566
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Schepetkin IA, Kirpotina LN, Khlebnikov AI, Hanks TS, Kochetkova I, Pascual DW, Jutila MA, Quinn MT:
Identification and Characterization of a Novel Class of c-Jun N-terminal Kinase Inhibitors
Mol Pharmacol. ;81(6):832-45
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Bostanci N, Belibasakis GN:
Doxycycline inhibits TREM-1 induction by Porphyromonas gingivalis
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Zaitseva M, Romantseva T, Blinova K, Beren J, Sirota L, Drane D, Golding H:
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Vaccine. 30: 4859-65
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Horvati K, Bacsa B, Szabo N, David S, Mezö G, Grolmusz V, Vertessy B, Hudecz F, Bösze S:
Enhanced Cellular Uptake of a New, in Silico Identified Antitubercular Candidate by Peptide Conjugation
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Hausmann M, Zeitler C, Weber A, Krebs M, Kellermeier S, Rosenstiel P, de Valliere C, Kosovac K, Fried M, Holler E, Rogler G.:
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Ochs MJ, Sorg BL, Pufahl L, Grez M, Suess B, Steinhilber D.:
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Carignan D, Desy O, de Campos-Lima PO.:
The dysregulation of the monocyte/macrophage effector function induced by isopropanol is mediated by the defective activation of distinct members of the AP-1 family of transcription factors
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Lok CA, Snijder KS, Nieuwland R, Van Der Post JA, de Vos P, Faas MM.:
Microparticles of pregnant women and preeclamptic patients activate endothelial cells in the presence of monocytes
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2012
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Spratt DA, Daglia M, Papetti A, Stauder M, O Donnell D, Ciric L, Tymon A, Repetto B, Signoretto C, Houri-Haddad Y, Feldman M, Steinberg D, Lawton S, Lingström P, Pratten J, Zaura E, Gazzani G, Pruzzo C, Wilson M.:
Evaluation of plant and fungal extracts for their potential antigingivitis and anticaries activity
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Leurs U, Lajko E, Mezo G, Orban E, Ohlschläger P, Marquardt A, Kohidai L, Manea M.:
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Eur J Med Chem.;52:173-83
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Lajko E, Polgar L, Lang O, Lengyel J, Köhidai L, Magyar K.:
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J Neural Transm. ;119(5):545-56
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Okuzaki D, Kimura S, Yabuta N, Ohmine T, Nojima H:
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BMC Clin Pathol. ;11:9
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Bostanci N, Thurnheer T, Belibasakis GN.:
Involvement of the TREM-1/DAP12 pathway in the innate immune responses to Porphyromonas gingivalis.
Mol Immunol. 49(1-2):387-94
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Pufahl L, Katryniok C, Schnur N, Sorg BL, Metzner J, Grez M, Steinhilber D.:
Trichostatin A induces 5-lipoxygenase promoter activity and mRNA expression via inhibition of histone deacetylase 2 and 3
J Cell Mol Med.; 16(7):1461-73
2011
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Kong Q, Six DA, Liu Q, Roland KL, Raetz CR, Curtiss R 3rd:
Palmitoylation state impacts innate and acquired immunity in the Salmonella enterica serovar Typhimurium msbB mutant
Infect Immun.;79(12):5027-38
2011
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Serwe A, Rudolph K, Anke T, Erkel G:
Inhibition of TGF-β signaling, vasculogenic mimicry and proinflammatory gene expression by isoxanthohumol
Invest New Drugs.;30(3):898-915
2011
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Huyton T, Göttmann W, Bade-Döding C, Paine A, Blasczyk R:
The T/NK cell co-stimulatory molecule SECTM1 is an IFN "early response gene" that is negatively regulated by LPS in Human monocytic cells
Biochim Biophys Acta.; 1810(12):1294-301
2011
Abstract PubMed
Kong Q, Six DA, Roland KL, Liu Q, Gu L, Reynolds CM, Wang X, Raetz CR, Curtiss R 3rd:
Salmonella synthesizing 1-monophosphorylated lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity
J Immunol. 187(1):412-23
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Jung M, Liermann JC, Opatz T, Erkel G:
Ganodermycin, a novel inhibitor of CXCL10 expression from Ganoderma applanatum
J Antibiot (Tokyo) ; 64(10):683-686
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Hansen C, Hansen EW, Hansen HR, Gammelgaard B, Stürup S.:
Reduction of Sb(V) in a Human Macrophage Cell Line Measured by HPLC-ICP-MS.
Biol Trace Elem Res.;144(1-3):234-43
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Howard KM, Abdel-Al M, Ditmyer M, Patel N:
Lipopolysaccharide and platelet-activating factor stimulate expression of platelet-activating factor acetylhydrolase via distinct signaling pathways
Inflamm Res.;60(8):735-44.
2011
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Sano C, Tatano Y, Shimizu T, Yamabe S, Sato K, Tomioka H:
Comparative in vitro and in vivo antimicrobial activities of sitafloxacin, gatifloxacin and moxifloxacin against Mycobacterium avium
Int J Antimicrob Agents. ;37(4):296-301
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Sarabi A, Kramp BK, Drechsler M, Hackeng TM, Soehnlein O, Weber C, Koenen RR, Von Hundelshausen P.:
CXCL4L1 inhibits angiogenesis and induces undirected endothelial cell migration without affecting endothelial cell proliferation and monocyte recruitment
J Thromb Haemost. ;9(1):209-19
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Witola WH, Mui E, Hargrave A, Liu S, Hypolite M, Montpetit A, Cavailles P, Bisanz C, Cesbron-Delauw MF, Fournie GJ, McLeod R:
NALP1 Influences Susceptibility to Human Congenital Toxoplasmosis, Proinflammatory Cytokine Response, and Fate of Toxoplasma gondii-Infected Monocytic Cells
Infect Immun. 79(2):756-66
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Mannonen L, Markkula E, Puolakkainen M:
Analysis of Chlamydia pneumoniae infection in mononuclear cells by reverse transcription-PCR targeted to chlamydial gene transcripts
Med Microbiol Immunol.; 200(3):143-54
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Vordenbäumen S, Braukmann A, Petermann K, Scharf A, Bleck E, von Mikecz A, Jose J, Schneider M:
Casein α s1 is expressed by human monocytes and upregulates the production of GM-CSF via p38 MAPK
J Immunol. ;186(1):592-601
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Jaimes Y, Seltsam A, Eiz-Vesper B, Blasczyk R, Figueiredo C:
Regulation of HLA class II expression prevents allogeneic T-cell responses
Tissue Antigens. 77:36-44.
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Esser J, Gehrmann U, Salvado MD, Wetterholm A, Haeggström JZ, Samuelsson B, Gabrielsson S, Scheynius A, Radmark O.:
Zymosan suppresses leukotriene C4 synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors
FASEB J. 25(4):1417-27
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Benfante R, Antonini RA, De Pizzol M, Gotti C, Clementi F, Locati M, Fornasari D.:
Expression of the α7 nAChR subunit duplicate form (CHRFAM7A) is down-regulated in the monocytic cell line THP-1 on treatment with LPS.
J Neuroimmunol. 230: 74-84
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Chakrabarty S, Snyder JT, Shen J, Azmi H, Hu PQ, Chen Q, Ragheb JA:
Human CD14hi monocytes and myeloid dendritic cells provide a cell contact-dependent costimulatory signal for early CD40 ligand expression
Blood.; 117(5):1585-94
2010
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Kraemer S, Lue H, Zernecke A, Kapurniotu A, Andreetto E, Frank R, Lennartz B, Weber C, Bernhagen J:
MIF-chemokine receptor interactions in atherogenesis are dependent on an N-loop-based 2-site binding mechanism
FASEB J.; 25(3):894-906
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Liu J, Pankhurst LJ, Deacon LJ, Abate W, Hayes ET, Drew GH, Longhurst PJ, Pollard S, Longhurst J, Tyrrel SF, Jackson SK:
Evaluation of inflammatory effects of airborne endotoxin emitted from composting sources
Environ Toxicol Chem.; 30(3):602-6
2010
Abstract PubMed
Faas MM, van Pampus MG, Anninga ZA, Salomons J, Westra IM, Donker RB, Aarnoudse JG, de Vos P:
Plasma from preeclamptic women activates endothelial cells via monocyte activation in vitro
J Reprod Immunol. ;87(1-2):28-38
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Szabó R, Bánóczi Z, Mező G, Láng O, Kőhidai L, Hudecz F.:
Daunomycin-polypeptide conjugates with antitumor activity.
Biochim Biophys Acta. 1798(12):2209-2216
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Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T.:
Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals.
FASEB J. 24(10):4089-102
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Krejbich-Trotot P, Denizot M, Hoarau JJ, Jaffar-Bandjee MC, Das T, Gasque P.:
Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses.
FASEB J.;25(1):314-25
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Lombard C, Farthing D, Sun J, Fariss MW, McKallip RJ.:
Reference moist smokeless tobacco-induced apoptosis in human monocytes/macrophages cell line MM6.
Int Immunopharmacol. 10(9):1029-40
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Richardson VJ.:
Divergent and synergistic regulation of matrix metalloprotease production by cytokines in combination with C-C chemokines.
Int J Immunopathol Pharmacol. 23(3):715-26
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Parihar A, Eubank TD, Doseff AI.:
Monocytes and macrophages regulate immunity through dynamic networks of survival and cell death.
J Innate Immun. 2(3):204-15
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Saaby L, Jäger AK, Moesby L, Hansen EW, Christensen SB.:
Isolation of immunomodulatory triterpene acids from a standardized rose hip powder (Rosa canina L.).
Phytother Res.; 25(2):195-201
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Szabo R, Banoczi Z, Mezö G, Lang O, Köhidai L, Hudecz F.:
Daunomycin-polypeptide conjugates with antitumor activity.
Biochim Biophys Acta.; 1798(12):2209-16
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Volz T, Nega M, Buschmann J, Kaesler S, Guenova E, Peschel A, Röcken M, Götz F, Biedermann T.:
Natural Staphylococcus aureus-derived peptidoglycan fragments activate NOD2 and act as potent costimulators of the innate immune system exclusively in the presence of TLR signals.
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Funk D, Sorg BL, Lindner SC, Schmeiser HH.:
(32)P-postlabeling analysis of DNA adducts formed by leukotriene A(4) (LTA(4)).
Environ Mol Mutagen. 51(4):338-43
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Moir H, Hughes MG, Potter S, Sims C, Butcher LR, Davies NA, Verheggen K, Jones KP, Thomas AW, Webb R.:
Exercise-induced Immunosuppression: The Roles of Reactive Oxygen Species and 5'AMP-activated Protein Kinase (AMPK) Dephosphorylation within Immune Cells.
J Appl Physiol.; 108(5):1284-92
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de Zoete MR, Keestra AM, Roszczenko P, van Putten JP.:
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Infect Immun. 78(3):1229-38
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Fransen F, Heckenberg SG, Hamstra HJ, Feller M, Boog CJ, van Putten JP, van de Beek D, van der Ende A, van der Ley P.:
Naturally occurring lipid A mutants in neisseria meningitidis from patients with invasive meningococcal disease are associated with reduced coagulopathy
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Jung M, Triebel S, Anke T, Richling E, Erkel G.:
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Mol Nutr Food Res. 53(10):1263-80
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Gawad A, Ptak-Belowska A, Brzozowski T, Pawlik WW.:
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J Physiol Pharmacol. 60(4):55-61
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Aravindan N, Shanmugasundaram K, Natarajan M.:
Hyperthermia induced NFkappaB mediated apoptosis in normal human monocytes.
Mol Cell Biochem. 327(1-2):29-37
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Breus VV, Heyes CD, Tron K, Nienhaus GU.:
Zwitterionic biocompatible quantum dots for wide pH stability and weak nonspecific binding to cells.
ACS Nano. 3(9):2573-80
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Merhi F, Auger J, Rendu F, Bauvois B.:
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Humphries J, Gossage JA, Modarai B, Burnand KG, Sisson TH, Murdoch C, Smith A.:
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J Vasc Surg. 50(5):1127-34.
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Esser J, Rakonjac M, Hofmann B, Fischer L, Provost P, Schneider G, Steinhilber D, Samuelsson B, Rådmark OP.:
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Biochem J. 425(1):265-74
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Stoffers KL, Sorg BL, Seuter S, Rau O, Rådmark O, Steinhilber D.:
Calcitriol Upregulates Open Chromatin and Elongation Markers at Functional Vitamin D Response Elements in the Distal Part of the 5-Lipoxygenase Gene.
J Mol Biol. 395(4):884-96
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Sung TL, Rice AP.:
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1.
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Huang LY, Dumontelle JL, Zolodz M, Deora A, Mozier NM, Golding B.:
Use of toll-like receptor assays to detect and identify microbial contaminants in biological products.
J Clin Microbiol. 47(11):3427-34
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Tahara T, Shibata T, Hirata I, Nakano H, Arisawa T.:
CD14 promoter-159 polymorphism is associated with reduced risk of intestinal-type gastric cancer in a Japanese population.
Dig Dis Sci. 54(7):1508-12
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Schimanski LM, Drakesmith H, Sweetland E, Bastin J, Rezgui D, Edelmann M, Kessler B, Merryweather-Clarke AT, Robson KJ, Townsend AR.:
In vitro binding of HFE to the cation-independent mannose-6 phosphate receptor.
Blood Cells Mol Dis. 43(2):180-93
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Romieu-Mourez R, François M, Boivin MN, Bouchentouf M, Spaner DE, Galipeau J.:
Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype.
J Immunol. 182(12):7963-73
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Schuh A, Liehn EA, Sasse A, Schneider R, Neuss S, Weber C, Kelm M, Merx MW.:
Improved left ventricular function after transplantation of microspheres and fibroblasts in a rat model of myocardial infarction.
Basic Res Cardiol. 104(4):403-11
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Rådmark O, Samuelsson B.:
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Bostanci N, Emingil G, Saygan B, Turkoglu O, Atilla G, Curtis MA, Belibasakis GN.:
Expression and regulation of the NALP3 inflammasome complex in periodontal diseases.
Clin Exp Immunol. 157(3):415-22
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Gross P, Brandl K, Dierkes C, Schölmerich J, Salzberger B, Glück T, Falk W.:
Lipopolysaccharide-trap-Fc, a multifunctional agent to battle gram-negative bacteria.
Infect Immun. 77(7):2925-31
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Geurtsen J, Dzieciatkowska M, Steeghs L, Hamstra HJ, Boleij J, Broen K, Akkerman G, El Hassan H, Li J, Richards JC, Tommassen J, van der Ley P.:
Identification of a novel lipopolysaccharide core biosynthesis gene cluster in Bordetella pertussis, and influence of core structure and lipid A glucosamine substitution on endotoxic activity.
Infect Immun. 77(7):2602-11
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Linz W, Wohlfart P, Baader M, Breitschopf K, Falk E, Schäfer HL, Gerl M, Kramer W, Rütten H.:
The peroxisome proliferator-activated receptor-alpha (PPAR-alpha) agonist, AVE8134, attenuates the progression of heart failure and increases survival in rats.
Acta Pharmacol Sin. 30(7):935-46
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Raby AC, Le Bouder E, Colmont C, Davies J, Richards P, Coles B, George CH, Jones SA, Brennan P, Topley N, Labéta MO.:
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J Immunol. 183(1):506-17
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Lindner SC, Köhl U, Maier TJ, Steinhilber D, Sorg BL.:
TLR2 ligands augment cPLA2alpha activity and lead to enhanced leukotriene release in human monocytes.
J Leukoc Biol. 86(2):389-99
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Maier TJ, Schiffmann S, Wobst I, Birod K, Angioni C, Hoffmann M, Lopez JJ, Glaubitz C, Steinhilber D, Geisslinger G, Grösch S.:
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J Mol Med. 87(10):981-93
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Sung TL, Rice AP.:
miR-198 inhibits HIV-1 gene expression and replication in monocytes and its mechanism of action appears to involve repression of cyclin T1.
PLoS Pathog. 5(1):e1000263
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Wu S, Barnes PF, Samten B, Pang X, Rodrigue S, Ghanny S, Soteropoulos P, Gaudreau L, Howard ST.:
Activation of the eis gene in a W-Beijing strain of Mycobacterium tuberculosis correlates with increased SigA levels and enhanced intracellular growth.
Microbiology. 155(Pt 4):1272-81
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Geurtsen J, Dzieciatkowska M, Steeghs L, Hamstra HJ, Boleij J, Broen K, Akkerman G, El Hassan H, Li J, Richards JC, Tommassen J, van der Ley P.:
IDENTIFICATION OF A NOVEL LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS GENE CLUSTER IN BORDETELLA PERTUSSIS: INFLUENCE OF CORE STRUCTURE AND LIPID A GLUCOSAMINE SUBSTITUTION ON ENDOTOXIC ACTIVITY.
Infect Immun. 77(7):2602-11
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Solakivi T, Kunnas T, Kärkkäinen S, Jaakkola O, Nikkari ST.:
Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells.
Lipids Health Dis. 8:11
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Dekker LJ, van Kampen JJ, Reedijk ML, Burgers PC, Gruters RA, Osterhaus AD, Luider TM.:
A mass spectrometry based imaging method developed for the intracellular detection of HIV protease inhibitors.
Rapid Commun Mass Spectrom. 23(8):1183-8.
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Adenuga D, Yao H, March TH, Seagrave J, Rahman I.:
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Am J Respir Cell Mol Biol. 40(4):464-73.
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Filip AM, Klug J, Cayli S, Fröhlich S, Henke T, Lacher P, Eickhoff R, Bulau P, Linder M, Carlsson-Skwirut C, Leng L, Bucala R, Kraemer S, Bernhagen J, Meinhardt A.:
Ribosomal Protein S19 Interacts with Macrophage Migration Inhibitory Factor and Attenuates Its Pro-inflammatory Function.
J Biol Chem. 284(12):7977-7985
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Asong J, Wolfert MA, Maiti KK, Miller D, Boons GJ.:
Binding and Cellular Activation Studies Reveal That Toll-like Receptor 2 Can Differentially Recognize Peptidoglycan from Gram-positive and Gram-negative Bacteria.
J Biol Chem. 284(13):8643-53
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Rådmark O, Samuelsson B.:
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J Lipid Res. 50 Suppl:S40-5
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Aravindan N, Shanmugasundaram K, Natarajan M.:
Hyperthermia induced NFkappaB mediated apoptosis in normal human monocytes.
Mol Cell Biochem. 327(1-2):29-37
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Nordigården A, Kraft M, Eliasson P, Labi V, Lam EW, Villunger A, Jönsson JI.:
BH3-only protein Bim more critical than Puma in tyrosine kinase inhibitor-induced apoptosis of human leukemic cells and transduced hematopoietic progenitors carrying oncogenic FLT3.
Blood. 113(10):2302-11.
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Hamedi M, Belibasakis GN, Cruchley AT, Rangarajan M, Curtis MA, Bostanci N.:
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Cytokine. 45(2):99-104
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Yang SR, Yao H, Rajendrasozhan S, Chung S, Edirisinghe I, Valvo S, Fromm G, McCabe MJ Jr, Sime PJ, Phipps RP, Li JD, Bulger M, Rahman I.:
RelB is differentially regulated by IkappaB Kinase-alpha in B cells and mouse lung by cigarette smoke.
Am J Respir Cell Mol Biol. 40(2):147-58
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Brännström K, Sellin ME, Holmfeldt P, Brattsand M, Gullberg M.:
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.
Infect Immun. 77(3):1144-54
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Faas MM, Donker RB, van Pampus MG, Huls AM, Salomons J, de Vos P, Aarnoudse JG:
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Hofer TP, Frankenberger M, Mages J, Lang R, Meyer P, Hoffmann R, Colige A, Ziegler-Heitbrock L.:
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J Mol Med. Mar;86(3):323-32
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Knockenhauer KE, Sawicka KM, Roemer EJ, Simon SR.:
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Santegoets SJ, van den Eertwegh AJ, van de Loosdrecht AA, Scheper RJ, de Gruijl TD.:
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J Leukoc Biol. 84(6):1364-73
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Timm M, Bartelt S, Hansen EW.:
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Cytokine. 42(1):113-20
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Popovic M, Laumonnier Y, Burysek L, Syrovets T, Simmet T.:
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Bai KB, LaÁng O, OrbaÁn E, SzaboÁ R, Köhidai L, Hudecz F, Mezö G.:
Design, Synthesis, and In Vitro Activity of Novel Drug Delivery Systems Containing Tuftsin Derivatives and Methotrexate.
Bioconjug Chem. 19(11):2260-9
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Siemoneit U, Hofmann B, Kather N, Lamkemeyer T, Madlung J, Franke L, Schneider G, Jauch J, Poeckel D, Werz O.:
Identification and functional analysis of cyclooxygenase-1 as a molecular target of boswellic acids.
Biochem Pharmacol. 75(2):503-13.
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Marantos C, Mukaro V, Ferrante J, Hii C, Ferrante A.:
Inhibition of the lipopolysaccharide-induced stimulation of the members of the MAPK family in human monocytes/macrophages by 4-hydroxynonenal, a product of oxidized omega-6 fatty acids.
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Jackson SK, Abate W, Parton J, Jones S, Harwood JL.:
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Tron K, Manolov DE, Röcker C, Kächele M, Torzewski J, Nienhaus GU.:
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Eur J Immunol. 38(5):1414-22.
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Lee J, Hwang J, Kim HS, Kim S, Kim YH, Park SY, Kim KS, Ryoo ZY, Chang KT, Lee S.:
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Identification of a strongly activating human anti-CD40 antibody that suppresses HIV type 1 infection.
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Shagdarsuren E, Bidzhekov K, Djalali-Talab Y, Liehn EA, Hristov M, Matthijsen RA, Buurman WA, Zernecke A, Weber C:
C1-esterase inhibitor protects against neointima formation after arterial injury in atherosclerosis-prone mice
Circulation., 117(1):70-78
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Nührenberg TG, Langwieser N, Schwarz JB, Hou Y, Frank P, Sorge F, Matschurat S, Seidl S, Kastrati A, Schömig A, Clauss MA, Zohlnhöfer D:
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Cardiovasc Res., 77(3):580-589
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Tretiakova I, Blaesius D, Maxia L, Wesselborg S, Schulze-Osthoff K, Cinatl J Jr, Michaelis M, Werz O:
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Caito S, Yang SR, Kode A, Edirisinghe I, Rajendrasozhan S, Phipps RP, Rahman I:
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Seuter S, Väisänen S, Rådmark O, Carlberg C, Steinhilber D:
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Bamford S, Ryley H, Jackson SK:
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Seitz I, Hess S, Schulz H, Eckl R, Busch G, Montens HP, Brandl R, Seidl S, Schomig A, Ott I:
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Biro A, Cervenak L, Balogh A, Lorincz A, Uray K, Horvath A, Romics L, Matko J, Fust G, Laszlo G:
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Spoettl T, Paetzel C, Herfarth H, Bencherif M, Schoelmerich J, Greinwald R, Gatto GJ, Rogler G:
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Fichtner-Feigl S, Strober W, Kawakami K, Puri RK, Kitani A.:
IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.
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Reindl C, Bagrintseva K, Vempati S, Schnittger S, Ellwart JW, Wenig K, Hopfner KP, Hiddemann W, Spiekermann K:
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Setzer F, Oberle V, Blass M, Moller E, Russwurm S, Deigner HP, Claus RA, Bauer M, Reinhart K, Losche W:
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Platelets, 17(8):571-576
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Haile WB, Coleman JL, Benach JL:
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Cassol E, Alfano M, Biswas P, Poli G:
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Lantow A, Viergutz T, Weiss DG, Simko M:
Comparative study of cell cycle kinetics and induction of apoptosis or necrosis after exposure of human mono mac 6 cells to radiofrequency radiation
Radiat Res., 166(3):539-43
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Garcia CS, Curiel RE, Mwatibo JM, Pestka S, Li H, Espinoza-Delgado I:
The antineoplastic agent bryostatin-1 differentially regulates IFN-gamma receptor subunits in monocytic cells: transcriptional and posttranscriptional control of IFN-gamma R2
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Saad AF, Virella G, Chassereau C, Boackle RJ, Lopes-Virella MF:
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Pahlman LI, Morgelin M, Eckert J, Johansson L, Russell W, Riesbeck K, Soehnlein O, Lindbom L, Norrby-Teglund A, Schumann RR, Bjorck L, Herwald H:
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Chauhan V, Mariampillai A, Gajda GB, Thansandote A, McNamee JP:
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Natarajan M, Nayak BK, Galindo C, Mathur SP, Roldan FN, Meltz ML:
Nuclear translocation and DNA-binding activity of NFKB (NF-kappaB) after exposure of human monocytes to pulsed ultra-wideband electromagnetic fields (1 kV/cm) fails to transactivate kappaB-dependent gene expression
Radiat Res., 165(6):645-654
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Yang SR, Chida AS, Bauter MR, Shafiq N, Seweryniak K, Maggirwar SB, Kilty I, Rahman I:
Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages
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Sorg BL, Klan N, Seuter S, Dishart D, Radmark O, Habenicht A, Carlberg C, Werz O, Steinhilber D:
Analysis of the 5-lipoxygenase promoter and characterization of a vitamin D receptor binding site
Biochim Biophys Acta (Molecular and Cell Biology of Lipids), 1761(7): 686-697
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Cusinato F, Pighin I, Luciani S, Trevisi L:
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Koch O, Kwiatkowski DP, Udalova IA:
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Blood, 107(8):3221-3228
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Majetschak M, Ponelies N, Hirsch T:
Targeting the monocytic ubiquitin system with extracellular ubiquitin
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Gauss KA, Bunger PL, Crawford MA, McDermott BE, Swearingen R, Nelson-Overton LK, Siemsen DW, Kobayashi SD, Deleo FR, Quinn MT:
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Gene, 366:169-179
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Schmidt R, Redecke V, Breitfeld Y, Wantia N, Miethke T, Massberg S, Fischel S, Neumann FJ, Schomig A, May AE:
EMMPRIN (CD 147) is a central activator of extracellular matrix degradation by Chlamydia pneumoniae-infected monocytes. Implications for plaque rupture
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LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO:
Modulation of Neonatal Microbial Recognition: TLR-Mediated Innate Immune Responses Are Specifically and Differentially Modulated by Human Milk
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Poeckel D, Tausch L, George S, Jauch J, Werz O:
3-O-acetyl-11-keto-boswellic acid decreases basal intracellular Ca2+ levels and inhibits agonist-induced Ca2+ mobilization and mitogen-activated protein kinase activation in human monocytic cells
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Schmidt R, Bueltmann A, Ungerer M, Joghetaei N, Bulbul O, Thieme S, Chavakis T, Toole BP, Gawaz M, Schomig A, May AE:
Extracellular matrix metalloproteinase inducer regulates matrix metalloproteinase activity in cardiovascular cells: implications in acute myocardial infarction
Circulation, 113(6): 834-84
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Radomska HS, Basseres DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG:
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Liang MD, Zhang Y, McDevit D, Marecki S, Nikolajczyk BS:
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Aleksandrov DA, Zagryagskaya AN, Pushkareva MA, Bachschmid M, Peters-Golden M, Werz O, Steinhilber D, Sud'ina GF:
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Martino V, Tonelli R, Montemurro L, Franzoni M, Marino F, Fazzina R, Pession A:
Down-regulation of MLL-AF9, MLL and MYC expression is not obligatory for monocyte-macrophage maturation in AML-M5 cell lines carrying t(9;11)(p22;q23)
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Dishart D, Schnur N, Klan N, Werz O, Steinhilber D, Samuelsson B, Radmark O:
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Biochim Biophys Acta (Molecular and Cell Biology of Lipids) 1738: 37-47
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Kocer SS, Walker SG, Zerler B, Golub LM, Simon SR:
Metalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cells
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Mause SF, von Hundelshausen P, Zernecke A, Koenen RR, Weber C:
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Legionella pneumophila down-regulates MHC class I expression of human monocytic host cells and thereby inhibits T cell activation
Cell Mol Life Sci., 62(5):578-588
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Stoll H, Dengjel J, Nerz C, Gotz F:
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Wieland H, Ullrich S, Lang F, Neumeister B:
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Gauss KA, Bunger PL, Larson TC, Young CJ, Nelson-Overton LK, Siemsen DW, Quinn MT:
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Ferrante JV, Ferrante A:
Cutting edge: Novel role of lipoxygenases in the inflammatory response: promotion of TNF mRNA decay by 15-hydroperoxyeicosatetraenoic acid in a monocytic cell line
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Ostermann G, Fraemohs L, Baltus T, Schober A, Lietz M, Zernecke A, Liehn EA, Weber C:
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Johnson BJ, Le TT, Dobbin CA, Banovic T, Howard CB, Flores Fde M, Vanags D, Naylor DJ, Hill GR, Suhrbier A:
Heat Shock Protein 10 Inhibits Lipopolysaccharide-induced Inflammatory Mediator Production
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Furnkranz A, Schober A, Bochkov VN, Bashtrykov P, Kronke G, Kadl A, Binder BR, Weber C, Leitinger N:
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Kempf VA, Schairer A, Neumann D, Grassl GA, Lauber K, Lebiedziejewski M, Schaller M, Kyme P, Wesselborg S, Autenrieth IB:
Bartonella henselae inhibits apoptosis in Mono Mac 6 cells
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Olwill SA, McGlynn H, Gilmore WS, Alexander HD:
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Baltus T, von Hundelshausen P, Mause SF, Buhre W, Rossaint R, Weber C:
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Scholl S, Krause C, Loncarevic IF, Muller R, Kunert C, Wedding U, Sayer HG, Clement JH, Hoffken K:
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Marino R, Deibis L, De Sanctis JB, Bianco NE, Toro F:
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Med Microbiol Immunol (Berl)., 194(1-2):73-80
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von Hundelshausen P, Koenen RR, Sack M, Mause SF, Adriaens W, Proudfoot AE, Hackeng TM, Weber C:
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Blood, 105(3):924-930
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Zhang J, McCrae KR:
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Blood, 105(5):1964-1969
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Koszalka P, Ozuyaman B, Huo Y, Zernecke A, Flogel U, Braun N, Buchheiser A, Decking UK, Smith ML, Sevigny J, Gear A, Weber AA, Molojavyi A, Ding Z, Weber C, Ley K, Zimmermann H, Godecke A, Schrader J:
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Lupke M, Rollwitz J, Simko M:
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Wottrich R, Diabate S, Krug HF:
Biological effects of ultrafine model particles in human macrophages and epithelial cells in mono- and co-culture
Int J Hyg Environ Health, 207(4):353-361
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Uray K, Medgyesi D, Hilbert A, Sarmay G, Gergely J, Hudecz F:
Synthesis and receptor binding of IgG1 peptides derived from the IgG Fc region
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Zhao XJ, Oliver P, Song K, Schurr J, Zhang Z, Kolls JK:
Chronic ethanol enhances ectodomain shedding in T cells and monocytes
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Safi H, Barnes PF, Lakey DL, Shams H, Samten B, Vankayalapati R, Howard ST:
IS6110 functions as a mobile, monocyte-activated promoter in Mycobacterium tuberculosis
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Turpaev K, Bouton C, Drapier JC:
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Szanto A, Benko S, Szatmari I, Balint BL, Furtos I, Ruhl R, Molnar S, Csiba L, Garuti R, Calandra S, Larsson H, Diczfalusy U, Nagy L:
Transcriptional Regulation of Human CYP27 Integrates Retinoid, Peroxisome Proliferator-Activated Receptor, and Liver X Receptor Signaling in Macrophages
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Grabiec A, Meng G, Fichte S, Bessler W, Wagner H, Kirschning CJ:
Human but not murine toll-like receptor 2 discriminates between tri-palmitoylated and tri-lauroylated peptides
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Irschick EU, Sgonc R, Bock G, Wolf H, Fuchs D, Nussbaumer W, Gottinger W, Huemer HP:
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Ophthalmic Res., 36(4):200-210
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Gerber A, Heimburg A, Reisenauer A, Wille A, Welte T, Buhling F:
Proteasome inhibitors modulate chemokine production in lung epithelial and monocytic cells
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Bounou S, Giguere JF, Cantin R, Gilbert C, Imbeault M, Martin G, Tremblay MJ:
The importance of virus-associated host ICAM-1 in human immunodeficiency virus type 1 dissemination depends on the cellular context
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Steeghs L, Tommassen J, Leusen JH, van de Winkel JG, van der Ley P:
Teasing apart structural determinants of 'toxicity' and 'adjuvanticity': implications for meningococcal vaccine development
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Ogawa K, Chen F, Kuang C, Chen Y:
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Fischer L, Steinhilber D, Werz O:
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Ding J, Umstead TM, Floros J, Phelps DS:
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Xu ZQ, Barrow WW, Suling WJ, Westbrook L, Barrow E, Lin YM, Flavin MT:
Anti-HIV natural product (+)-calanolide A is active against both drug-susceptible and drug-resistant strains of Mycobacterium tuberculosis
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Rubic T, Trottmann M, Lorenz RL:
Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin
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Feisst C, Werz O:
Suppression of receptor-mediated Ca2+ mobilization and functional leukocyte responses by hyperforin
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Takabayashi T, Shimizu S, Clark BD, Beinborn M, Burke JF, Gelfand JA:
Interleukin-1 upregulates anaphylatoxin receptors on mononuclear cells
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Neumeister B:
Intracellular Multiplication of Legionella Species and the Influence of Amoebae on Their Intracellular Growth in Human Monocytes: Mono Mac 6 Cells and Acanthamoeba castellanii as Suitable In Vitro Models
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Wieland H, Goetz F, Neumeister B:
Phagosomal acidification is not a prerequisite for intracellular multiplication of Legionella pneumophila in human monocytes
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Demanet C, Mulder A, Deneys V, Worsham MJ, Maes P, Claas FH, Ferrone S:
Down-regulation of HLA-A and HLA-Bw6, but not HLA-Bw4, allospecificities in leukemic cells: an escape mechanism from CTL and NK attack?
Blood, 103:3122-3130
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Marshall AS, Willment JA, Lin HH, Williams DL, Gordon S, Brown GD:
Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes
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Drexler HG, Quentmeier H, MacLeod RA:
Malignant hematopoietic cell lines: in vitro models for the study of MLL gene alterations
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Zohlnhöfer D, Nuhrenberg TG, Neumann FJ, Richter T, May AE, Schmidt R, Denker K, Clauss MA, Schomig A, Baeuerle PA:
Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties
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Schober A, Bernhagen J, Thiele M, Zeiffer U, Knarren S, Roller M, Bucala R, Weber C:
Stabilization of atherosclerotic plaques by blockade of macrophage migration inhibitory factor after vascular injury in apolipoprotein E-deficient mice
Circulation, 109:380-385
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Steinberger P, Majdic O, Derdak SV, Pfistershammer K, Kirchberger S, Klauser C, Zlabinger G, Pickl WF, Stockl J, Knapp W:
Molecular Characterization of Human 4Ig-B7-H3, a Member of the B7 Family with Four Ig-Like Domains
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Fraemohs L, Koenen RR, Ostermann G, Heinemann B, Weber C:
The functional interaction of the beta2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain
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Brandt R, Nawka M, Kellermann J, Salazar R, Becher D, Krantz S:
Nucleophosmin is a component of the fructoselysine-specific receptor in cell membranes of Mono Mac 6 and U937 monocyte-like cells
Biochim Biophys Acta (General Subjects) 1670: 132-136
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Gebbia JA, Coleman JL, Benach JL:
Selective induction of matrix metalloproteinases by Borrelia burgdorferi via toll-like receptor 2 in monocytes
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Vitale S, Schmid-Alliana A, Breuil V, Pomeranz M, Millet MA, Rossi B, Schmid-Antomarchi H.:
Soluble fractalkine prevents monocyte chemoattractant protein-1-induced monocyte migration via inhibition of stress-activated protein kinase 2/p38 and matrix metalloproteinase activities
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Altmann A, Poeckel D, Fischer L, Schubert-Zsilavecz M, Steinhilber D, Werz O.:
Coupling of boswellic acid-induced Ca2+ mobilisation and MAPK activation to lipid metabolism and peroxide formation in human leucocytes
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Mannonen L, Kamping E, Penttila T, Puolakkainen M:
IFN-gamma induced persistent Chlamydia pneumoniae infection in HL and Mono Mac 6 cells: characterization by real-time quantitative PCR and culture
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Kirchner S, Boldt S, Kolch W, Haffner S, Kazak S, Janosch P, Holler E, Andreesen R, Eissner G:
LPS resistance in monocytic cells caused by reverse signaling through transmembrane TNF (mTNF) is mediated by the MAPK/ERK pathway
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Wang R, Stephens J, Lacy MJ:
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Pham TN, Brown BL, Dobson PR, Richardson VJ:
Protein kinase C-eta (PKC-eta) is required for the development of inducible nitric oxide synthase (iNOS) positive phenotype in human monocytic cells
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Arkel YS, Ku DH, Thurston AL:
The effect of thalidomide on tissue factor activity in Mono Mac 6 cells and the relationship to tumor necrosis factor (TNF)-alpha-stimulated cells
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Schulz S, Birkenmeier G, Schagdarsurengin U, Wenzel K, Muller-Werdan U, Rehfeld D, Suss T, Kabisch A, Werdan K, Glaser C:
Role of LDL receptor-related protein (LRP) in coronary atherosclerosis
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Wahl C, Maier S, Marre R, Essig A.:
Chlamydia pneumoniae induces the expression of inhibitor of apoptosis 2 (c-IAP2) in a human monocytic cell line by an NF-kB-dependent pathway
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LeBouder E, Rey-Nores JE, Rushmere NK, Grigorov M, Lawn SD, Affolter M, Griffin GE, Ferrara P, Schiffrin EJ, Morgan BP, Labeta MO:
Soluble forms of toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milk
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Barrow EW, Westbrook L, Bansal N, Suling WJ, Maddry JA, Parker WB, Barrow WW:
Antimycobacterial activity of 2-methyl-adenosine
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Fuentes L, Perez R, Nieto ML, Balsinde J, Balboa MA:
Bromoenol lactone promotes cell death by a mechanism involving phosphatidate phosphohydrolase-1 rather than calcium-independent phospholipase A2
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Coleman JL, Benach JL:
The Urokinase Receptor Can Be Induced by Borrelia burgdorferi through Receptors of the Innate Immune System
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Baltus T, Weber KS, Johnson Z, Proudfoot AE, Weber C:
Oligomerization of RANTES is required for CCR1-mediated arrest but not CCR5-mediated transmigration of leukocytes on inflamed endothelium
Blood, 102(6):1985-8
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Kato M, Khan S, Gonzalez N, O'Neill BP, McDonald KJ, Cooper BJ, Angel NZ, Hart DN:
Hodgkin's Lymphoma Cell Lines Express a Fusion Protein Encoded by Intergenically Spliced mRNA for the Multilectin Receptor DEC-205 (CD205) and a Novel C-type Lectin Receptor DCL-1
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Jimenez-Sainz MC, Fast B, Mayor F Jr, Aragay AM:
Signaling pathways for monocyte chemoattractant protein 1-mediated extracellular signal-regulated kinase activation
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Shatrov VA, Brune B:
Induced expression of manganese superoxide dismutase by non toxic concentrations of oxidized low density lipoprotein (oxLDL) protects against oxLDL-mediated cytotoxicity
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Buerkert E, Arnold C, Hammarberg T, Radmark O, Steinhilber D, Werz O:
The C2-like b-barrel domain mediates the Ca2+-dependent resistance of 5-lipoxygenase activity against inhibition by glutathione peroxidase-1
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Ohata A, Usami M, Horiuchi T, Nagasawa K, Kinoshita K:
Release of (1-->3)-beta-D-Glucan from Depth-type Membrane Filters and Their In Vitro Effects on Proinflammatory Cytokine Production
Artif Organs., 27(8):728-35
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Breuil V, Schmid-Antomarchi H, Schmid-Alliana A, Rezzonico R, Euller-Ziegler L, Rossi B:
The receptor activator of nuclear factor (NF)κB ligand (RANKL) is a new chemotactic factor for human monocytes
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Nilsen AM, Hagemann R, Eikas H, Egeberg K, Norkov T, Sundan A:
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Moesby L, Hansen EW, Christensen JD, Tommerup L, Nielsen C::
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Sato K, Tomioka H, Sano C, Shimizu T, Sano K, Ogasawara K, Cai S, Kamei T:
Comparative antimicrobial activities of gatifloxacin, sitafloxacin and levofloxacin against Mycobacterium tuberculosis replicating within Mono Mac 6 human macrophage and A-549 type II alveolar cell lines
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Tonks AJ, Tonks A, Morris RH, Jones KP, Jackson SK:
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Van Der Ley P, Steeghs L:
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Nakagawa Y, Murai T, Hasegawa C, Hirata M, Tsuchiya T, Yagami T, Haishima Y:
Endotoxin contamination in wound dressings made of natural biomaterials
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Tonks AJ, Cooper RA, Jones KP, Blair S, Parton J, Tonks A:
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Schmid B, Finnen MJ, Harwood JL, Jackson SK:
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Spiekermann K, Bagrintseva K, Schwab R, Schmieja K, Hiddemann W:
Overexpression and constitutive activation of FLT3 induces STAT5 activation in primary acute myeloid leukemia blast cells
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Klan N, Seuter S, Schnur N, Jung M, Steinhilber D:
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Strobach D, Lorenz RL:
The bisphosphonate ibandronate stimulates reverse cholesterol transport out of monocytoid cells by enhanced ABCA1 transcription
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Lauber K, Bohn E, Kröber SM, Xiao Y, Blumenthal SG, Lindemann RK, Marini P, Wiedig C, Zobywalski A, Baksh S, Xu Y, Autenrieth IB, Schulze-Osthoff K, Belka K, Stuhler G, Wesselborg S:
Apoptotic Cells Induce Migration of Phagocytes via Caspase-3-Mediated Release of a Lipid Attraction Signal
Cell 113, 717-730
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Zernecke A, Erl W, Fraemohs L, Lietz M, Weber C:
Suppression of endothelial adhesion molecule up-regulation with cyclopentenone prostaglandins is dissociated from IkappaB-alpha kinase inhibition and cell death induction
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Vyas K, Brassard DL, DeLorenzo MM, Sun Y, Grace MJ, Borden EC, Leaman DW:
Biologic Activity of Polyethylene Glycol12000-Interferon-alpha2b Compared with Interferon-alpha2b: Gene Modulatory and Antigrowth Effects in Tumor Cells
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Tsutsumi-Ishii Y, Nagaoka I:
Modulation of Human beta-Defensin-2 Transcription in Pulmonary Epithelial Cells by Lipopolysaccharide-Stimulated Mononuclear Phagocytes Via Proinflammatory Cytokine Production
J Immunol 170: 4226-4236
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Lee JY, Kim NA, Sanford A, Sullivan KE:
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Schwartz LB, Min HK, Ren S, Xia HZ, Hu J, Zhao W, Moxley G, Fukuoka Y:
Tryptase Precursors Are Preferentially and Spontaneously Released, Whereas Mature Tryptase Is Retained by HMC-1 Cells, Mono-Mac-6 Cells, and Human Skin-Derived Mast Cells
J Immunol 170: 5667-5673
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Huo Y, Schober A, Forlow SB, Smith DF, Hyman MC, Jung S, Littman DR, Weber C, Ley K:
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E
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May AE, Redecke V, Gruner S, Schmidt R, Massberg S, Miethke T, Ryba B, Prazeres Da Costa C, Schomig A, Neumann FJ:
Recruitment of Chlamydia pneumoniae-Infected Macrophages to the Carotid Artery Wall in Noninfected, Nonatherosclerotic Mice
Arterioscler Thromb Vasc Biol 23: 789-794
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Zhao XJ, Marrero L, Song K, Oliver P, Chin SY, Simon H, Schurr JR, Zhang Z, Thoppil D, Lee S, Nelson S, Kolls JK:
Acute Alcohol Inhibits TNF-alpha Processing in Human Monocytes by Inhibiting TNF/TNF-alpha-Converting Enzyme Interactions in the Cell Membrane
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Weissgerber P, Faigle M, Northoff H, Neumeister B:
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Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: Almost identical MLL breakpoints in therapy-related AML after treatment without etoposides
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Neurauter G, Wirleitner B, Laich A, Schennach H, Weiss G, Fuchs D:
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Burkert E, Szellas D, Radmark O, Steinhilber D, Werz O:
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Surfactant Protein A and D Differently Regulate the Immune Response to Nonmucoid Pseudomonas aeruginosa and Its Lipopolysaccharide
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Barthel R, Tsytsykova AV, Barczak AK, Tsai EY, Dascher CC, Brenner MB, Goldfeld AE:
Regulation of Tumor Necrosis Factor Alpha Gene Expression by Mycobacteria Involves the Assembly of a Unique Enhanceosome Dependent on the Coactivator Proteins CBP/p300
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2002
Abstract PubMed
Danz H, Stoyanova S, Thomet OA, Simon HU, Dannhardt G, Ulbrich H, Hamburger M:
Inhibitory activity of tryptanthrin on prostaglandin and leukotriene synthesis
Planta Med 68: 875-880
2002
Abstract PubMed
Stroh C, Cassens U, Samraj AK, Sibrowski W, Schulze-Osthoff K, Los M:
The role of caspases in cryoinjury: caspase inhibition strongly improves the recovery of cryopreserved hematopoietic and other cells
FASEB J 16: 1651-1653
2002
Abstract PubMed
Sing A, Rost D, Tvardovskaia N, Roggenkamp A, Wiedemann A, Kirschning CJ, Aepfelbacher M, Heesemann J:
Yersinia V-antigen exploits toll-like receptor 2 and CD14 for interleukin 10-mediated immunosuppression
J Exp Med 196: 1017-1024
2002
Abstract PubMed
Schober A, Manka D, von Hundelshausen P, Huo Y, Hanrath P, Sarembock IJ, Ley K, Weber C:
Deposition of platelet RANTES triggering monocyte recruitment requires P-selectin and is involved in neointima formation after arterial injury
Circulation 106: 1523-1529
2002
Abstract PubMed
Natarajan M, Aravindan N, Meltz ML, Herman TS:
Post-translational modification of I-kappa B alpha activates NF-kappa B in human monocytes exposed to 56Fe ions
Radiat Environ Biophys 41: 139-144
2002
Abstract PubMed
Schulte CE, Lindern Mv M, Steinlein P, Beug H, Wiedemann LM:
MLL-ENL cooperates with SCF to transform primary avian multipotent cells
EMBO J 21: 4297-4306
2002
Abstract PubMed
Vandenplas ML, Carlson RW, Jeyaretnam BS, McNeill B, Barton MH, Norton N, Murray TF, Moore JN:
Rhizobium sin-1 LPS prevents enteric LPS-induced cytokine production by mono Mac 6 cells
J Biol Chem 277: 41811-41816
2002
Abstract PubMed
Werz O, Bürkert E, Fischer L, Szellas D, Dishart D, Samuelsson B, Rådmark O, Steinhilber D:
Extracellular signal-regulated kinases phosphorylate 5-lipoxygenase and stimulate 5-lipoxygenase product formation in leukocytes
FASEB J 16: 1441-1443
2002
Abstract PubMed
May AE, Schmidt R, Kanse SM, Chavakis T, Stephens RW, Schomig A, PreissnerKT, Neumann FJ:
Urokinase Receptor Surface Expression Regulates Monocyte Adhesion in Acute Myocardial Infarction
Blood 100: 3611-3617
2002
Abstract PubMed
Kerkhoff C, Hofmann HA, Vormoor J, Melkonyan H, Roth J, Sorg C, Klempt M:
Binding of two nuclear complexes to a novel regulatory element within the human S100A9 promoter drives the S100A9 gene expression
J Biol Chem 277: 41879-41887
2002
Abstract PubMed
Cervino AC, Lakiss S, Sow O, Bellamy R, Beyers N, Hoal-Van Helden E, Van Helden P, McAdam KP, Hill AV:
Fine mapping of a putative tuberculosis-susceptibility locus on chromosome 15q11-13 in African families
Hum Mol Genet 11: 1599-1603
2002
Abstract PubMed
Soto D, Malmsten C, Blount JL, Muilenburg DJ, Caughey GH:
Genetic deficiency of human mast cell a-tryptase
Clin Exp Allergy 32: 1000-1006
2002
Abstract PubMed
Wieland H, Faigle M, Lang F, Northoff H, Neumeister B:
Regulation of the Legionella mip-promotor during infection of human monocytes
FEMS Microbiol Lett 212: 127-132
2002
Abstract PubMed
Burkert E, Radmark O, Steinhilber D, Werz O:
Monocyte-derived soluble protein confers 5-lipoxygenase activity Ca2+-dependent
Biochem Biophys Res Commun 295: 985-991
2002
Abstract PubMed
Triantafilou M, Miyake K, Golenbock DT, Triantafilou K:
Mediators of innate immune recognition of bacteria concentrate in lipid rafts and facilitate lipopolysaccharide-induced cell activation
J Cell Sci 115: 2603-2611
2002
Abstract PubMed
Wolfert MA, Murray TF, Boons GJ, Moore JN:
The origin of the synergistic effect of muramyldipeptide with endotoxin and peptidoglycan
J Biol Chem 277: 39179-39186
2002
Abstract PubMed
Nakagawa Y, Maeda H, Murai T:
Evaluation of the in vitro pyrogen test system based on proinflammatory cytokine release from human monocytes: comparison with a human whole blood culture test system and with the rabbit pyrogen test
Clin Diagn Lab Immunol 9: 588-597
2002
Abstract PubMed
Haehnel V, Schwarzfischer L, Fenton MJ, Rehli M:
Transcriptional regulation of the human toll-like receptor 2 gene in monocytes and macrophages
J Immunol 168: 5629-5637
2002
Abstract PubMed
Van Heel DA, Udalova IA, De Silva AP, McGovern DP, Kinouchi Y, Hull J, Lench NJ, Cardon LR, Carey AH, Jewell DP, Kwiatkowski D:
Inflammatory bowel disease is associated with a TNF polymorphism that affects an interaction between the OCT1 and NF-kappaB transcription factors
Hum Mol Genet 11:1281-1289
2002
Abstract PubMed
Kwakkenbos MJ, Chang GW, Lin HH, Pouwels W, de Jong EC, van Lier RA, Gordon S, Hamann J:
The human EGF-TM7 family member EMR2 is a heterodimeric receptor expressed on myeloid cells
J Leukoc Biol 71: 854-862
2002
Abstract PubMed
Swinney DC, Xu YZ, Scarafia LE, Lee I, Mak AY, Gan QF, Ramesha CS, Mulkins MA, Dunn J, So OY, Biegel T, Dinh M, Volkel P, Barnett J, Dalrymple SA, Lee S, Huber M:
A small molecule ubiquitination inhibitor blocks NF-kappa B-dependent cytokine expression in cells and rats
J Biol Chem 277: 23573-23581
2002
Abstract PubMed
Lehmann T, Murphy C, Zahra DG, Handel ML:
Reduction of tumor necrosis factor induced nuclear factor-kappaB nuclear translocation and DNA binding by dexamethasone in human osteoarthritic synovial tissue explants
J Rheumatol 29: 787-795
2002
Abstract PubMed
Natarajan M, V V, Szilagyi M, Roldan FN, Meltz ML:
NF-kappaB DNA-binding activity after high peak power pulsed microwave (8.2 GHz) exposure of normal human monocytes.
Bioelectromagnetics 23: 271-277
2002
Abstract PubMed
Sato K, Tomioka H, Shimizu T, Gonda T, Ota F, Sano C:
Type II Alveolar Cells Play Roles in Macrophage-Mediated Host Innate Resistance to Pulmonary Mycobacterial Infections by Producing Proinflammatory Cytokines
J Infect Dis 185: 1139-1147
2002
Abstract PubMed
Mack M, Pfirstinger J, Weber C, Weber KS, Nelson PJ, Rupp T, Maletz K, Bruhl H, Schlondorff D:
Chondroitin sulfate A released from platelets blocks RANTES presentation on cell surfaces and RANTES-dependent firm adhesion of leukocytes
Eur J Immunol 32: 1012-1020
2002
Abstract PubMed
Kroesen B-J, McLaughlin P M J, Schuilenga-Hut P H L, Jacobs S C, Molema G, Helfrich W, De Leij L F M H:
Tumor-targeted immune complex formation: Effects on myeloid cell activation and tumor-directed immune cell migration
Int J of Cancer 98: 857-863
2002
Abstract PubMed
Burkert E, Radmark O, Samuelsson B, Steinhilber D, Werz O:
Hypertonicity suppresses ionophore-induced product formation and translocation of 5-lipoxygenase in human leukocytes
J Leukoc Biol 71: 477-486
2002
Abstract PubMed
Werz O, Szellas D, Steinhilber D, Radmark O:
Arachidonic acid promotes phosphorylation of 5-lipoxygenase at Ser-271 by MAPK-activated protein kinase 2 (MK2)
J Biol Chem; 277(17):14793-800
2002
Abstract PubMed
Tomioka H, Sato K, Sano C, Sano K, Shimizu T:
Intramacrophage passage of Mycobacterium tuberculosis and M. avium complex alters the drug susceptibilities of the organisms as determined by intracellular susceptibility testing using macrophages and type II alveolar epithelial cells.
Antimicrob Agents Chemother 46: 519-521
2002
Abstract PubMed
Lee HA, Hughes DA:
Alpha-lipoic acid modulates NF-kappaB activity in human monocytic cells by direct interaction with DNA
Exp Gerontol 37: 401-410
2002
Abstract PubMed
Burke B, Tang N, Corke KP, Tazzyman D, Ameri K, Wells M, Lewis CE:
Expression of HIF-1alpha by human macrophages: implications for the use of macrophages in hypoxia-regulated cancer gene therapy
J Pathol 196: 204-212
2002
Abstract PubMed
Jostarndt K, Gellert N, Rubic T, Weber C, Kuhn H, Johansen B, Hrboticky N, Neuzil J:
Dissociation of Apoptosis Induction and CD36 Upregulation by Enzymatically
Biochem Biophys Res Commun 290: 988-93
2002
Abstract PubMed
Sing A, Roggenkamp A, Geiger AM, Heesemann J.:
Yersinia enterocolitica Evasion of the Host Innate Immune Response by V Antigen-Induced IL-10 Production of Macrophages Is Abrogated in IL-10-Deficient Mice
J Immunol 168: 1315-21
2002
Abstract PubMed
Burkart V, Kim YE, Hartmann B, Ghiea I, Syldath U, Kauer M, Fingberg W, Hanifi-Moghaddam P, Muller S, Kolb H.:
Cholera Toxin B Pretreatment of Macrophages and Monocytes Diminishes Their Proinflammatory Responsiveness to Lipopolysaccharide
J Immunol 168: 1730-1737
2002
Abstract PubMed
Uhl J, Klan N, Rose M, Entian KD, Werz O, Steinhilber D:
The 5-lipoxygenase promoter is regulated by DNA methylation
J Biol Chem., 277(6):4374-4379
2002
Abstract PubMed
Salazar R, Brandt R, Krantz S:
Binding of Amadori glucose-modified albumin by the monocytic cell line MonoMac 6 activates protein kinase C varepsilon protein tyrosine kinases and the transcription factors AP-1 and NF-kappaB
Glycoconj J 18: 769-777
2001
Abstract PubMed
Weber KS, Weber C, Ostermann G, Dierks H, Nagel W, Kolanus W:
Cytohesin-1 is a dynamic regulator of distinct LFA-1 functions in leukocyte arrest and transmigration triggered by chemokines
Curr Biol 11: 1969-1974
2001
Abstract PubMed
Randow F, Seed B:
Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability
Nat Cell Biol 3: 891-896
2001
Abstract PubMed
Zernecke A, Weber KS, Weber C:
Combined modulation of the mesangial machinery for monocyte recruitment by inhibition of NF-kappaB
Am J Physiol Cell Physiol 281: C1881-C1888
2001
Abstract PubMed
Bonder CS, Hart PH, Davies KV, Burkly LC, Finlay-Jones JJ, Woodcock JM:
Characterization of IL-4 receptor components expressed on monocytes and monocyte-derived macrophages: variation associated with differential signaling by IL-4
Growth Factors 19: 207-218
2001
Abstract PubMed
Pereira HA:
Cationic antimicrobial protein of Mr 37 kDa: a multifunctional inflammatory protein
Chin Med J (Engl) 114: 9-13
2001
Abstract PubMed
Wahl C, Oswald F, Simnacher U, Weiss S, Marre R, Essig A:
Survival of Chlamydia pneumoniae-Infected Mono Mac 6 Cells Is Dependent on NF-kappaB Binding Activity
Infect Immun 69:7039-7045
2001
Abstract PubMed
Elms J, Beckett PN, Griffin P, Curran AD:
Mechanisms of isocyanate sensitisation. An in vitro approach
Toxicol In Vitro 15: 631-634
2001
Abstract PubMed
Schupp P, Steube K, Meyer C, Proksch P:
Anti-proliferative effects of new staurosporine derivatives isolated from a marine ascidian and its predatory flatworm
Cancer Lett 174:165-172
2001
Abstract PubMed
LeVan TD, Bloom JW, Bailey TJ, Karp CL, Halonen M, Martinez FD, Vercelli D:
A common single nucleotide polymorphism in the CD14 promoter decreases the affinity of Sp protein binding and enhances transcriptional activity
J Immunol 167:5838-5844
2001
Abstract PubMed
Stoyanova E, Tesch A, Armstrong VW, Wieland E:
Enzymatically degraded low density lipoproteins are more potent inducers of egr-1 mRNA than oxidized or native low density lipoproteins
Clin Biochem 34:483-490
2001
Abstract PubMed
Triantafilou K, Triantafilou M, Dedrick RL:
A CD14-independent LPS receptor cluster
Nat Immunol 2:338-345
2001
Abstract PubMed
Skovronsky DM, Fath S, Lee VM, Milla ME:
Neuronal localization of the TNFalpha converting enzyme (TACE) in brain tissue and its correlation to amyloid plaques
J Neurobiol 49:40-46
2001
Abstract PubMed
Ogbourne SM, Antalis TM:
Characterisation of PAUSE-1, a powerful silencer in the human plasminogen activator inhibitor type 2 gene promoter
Nucleic Acids Res 29:3919-3927
2001
Abstract PubMed
van der Ley P, Steeghs L, Hamstra HJ, ten Hove J, Zomer B, van Alphen L:
Modification of lipid A biosynthesis in Neisseria meningitidis lpxL mutants: influence on lipopolysaccharide structure, toxicity, and adjuvant activity
Infect Immun 69:5981-5990
2001
Abstract PubMed
Huo Y, Weber C, Forlow SB, Sperandio M, Thatte J, Mack M, Jung S, Littman DR, Ley K:
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium
J Clin Invest 108:1307-1314
2001
Abstract PubMed
Conway JG, Andrews RC, Beaudet B, Bickett DM, Boncek V, Brodie TA, Clark RL, Crumrine RC, Leenitzer MA, McDougald DL, Han B, Hedeen K, Lin P, Milla M, Moss M, Pink H, Rabinowitz MH, Tippin T, Scates PW, Selph J, Stimpson SA, Warner J, Becherer JD:
Inhibition of tumor necrosis factor-alpha (TNF-alpha) production and arthritis in the rat by GW3333, a dual inhibitor of TNF-alpha-converting enzyme and matrix metalloproteinases
J Pharmacol Exp Ther 298:900-908
2001
Abstract PubMed
Brown DM, Wilson MR, MacNee W, Stone V, Donaldson K:
Size-dependent proinflammatory effects of ultrafine polystyrene particles: a role for surface area and oxidative stress in the enhanced activity of ultrafines
Toxicol Appl Pharmacol 175:191-199
2001
Abstract PubMed
Neumeister B, Bach V, Faigle M, Northoff H:
Induction of iNOS in human monocytes infected with different Legionella species
FEMS Microbiol Lett 202: 31-38
2001
Abstract PubMed
Dinkelmann S, Rohlke W, Meinert H, Northoff H:
A system establishment compatibility profiles for artificial oxygen carriers and other substances
Artif Cells Blood Substit Immobil Biotechnol 29: 57-70
2001
Abstract PubMed
Danz H, Stoyanova S, Wippich P, Brattstrom A, Hamburger M:
Identification and isolation of the cyclooxygenase-2 inhibitory principle in Isatis tinctoria
Planta Med 67: 411-416
2001
Abstract PubMed
Ross HL, Nonnemacher MR, Hogan TH, Quiterio SJ, Henderson A, McAllister JJ, Krebs FC, Wigdahl B:
Interaction between CCAAT/enhancer binding protein and cyclic AMP response element binding protein 1 regulates human immunodeficiency virus type 1 transcription in cells of the monocyte/macrophage lineage
J Virol 75: 1842-1856
2001
Abstract PubMed
Vidal VF, Casteran N, Riendeau CJ, Kornfeld H, Darcissac EC, Capron A, Bahr GM:
Macrophage stimulation with Murabutide, an HIV-suppressive muramyl peptide derivative, selectively activates extracellular signal-regulated kinases 1 and 2, C/EBPbeta and STAT1: role of CD14 and Toll-like receptors 2 and 4
Eur J Immunol 31: 1962-1971
2001
Abstract PubMed
Woltman AM, de Fijter JW, Kamerling SW, van Der Kooij SW, Paul LC, Daha MR, van Kooten C:
Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages
Blood 98: 174-180
2001
Abstract PubMed
Tonks A, Cooper RA, Price AJ, Molan PC, Jones KP:
Stimulation of tnf-alpha release in monocytes by honey
Cytokine 14: 240-242
2001
Abstract PubMed
Yang Z, Tao T, Raftery MJ, Youssef P, Di Girolamo N, Geczy CL:
Proinflammatory properties of the human S100 protein S100A12
J Leukoc Biol 69: 986-994
2001
Abstract PubMed
von Hundelshausen P, Weber KS, Huo Y, Proudfoot AE, Nelson PJ, Ley K, Weber C:
RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium
Circulation 103: 1772-1777
2001
Abstract PubMed
Haishima Y, Murai T, Nakagawa Y, Hirata M, Yagami T, Nakamura A:
Chemical and biological evaluation of endotoxin contamination on natural rubber latex products
J Biomed Mater Res (Part A) 55: 424-32
2001
Abstract PubMed
Ali SA, Stoeva S, Abbasi A, Alam JM, Kayed R, Faigle M, Neumeister B, Voelter W:
Isolation, structural, and functional characterization of an apoptosis-inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom
Arch Biochem Biophys 384: 216-226
2001
Abstract PubMed
Lee JY, Sullivan KE:
Gamma interferon and lipopolysaccharide interact at the level of transcription to induce tumor necrosis factor alpha expression
Infect Immun 69: 2847-2852
2001
Abstract PubMed
Tonks A, Morris RH, Price AJ, Thomas AW, Jones KP, Jackson SK:
Dipalmitoylphosphatidylcholine modulates inflammatory functions of monocytic cells independently of mitogen activated protein kinases
Clin Exp Immunol 124: 86-94
2001
Abstract PubMed
Gorbacheva VY, Faundez G, Godfrey HP, Cabello FC:
Restricted growth of ent- and tonB mutants of Salmonella enterica serovar Typhi in human Mono Mac 6 monocytic cells
FEMS Microbiol Lett 196: 7-11
2001
Abstract PubMed
Werz O, Klemm J, Samuelsson B, Radmark O:
Phorbol ester up-regulates capacities for nuclear translocation and phosphorylation of 5-lipoxygenase in Mono Mac 6 cells and human polymorphonuclear leukocytes
Blood 97: 2487-2495
2001
Abstract PubMed
Musso T, Deaglio S, Franco L, Calosso L, Badolato R, Garbarino G, Dianzani U, Malavasi F:
CD38 expression and functional activities are up-regulated by IFN-g on human monocytes and monocytic cell lines
J Leukoc Biol 69: 605-612
2001
Abstract PubMed
Vaday GG, Schor H, Rahat MA, Lahat N, Lider O:
Transforming growth factor-beta suppresses tumor necrosis factor alpha-induced matrix metalloproteinase-9 expression in monocytes
J Leukoc Biol 69: 613-621
2001
Abstract PubMed
Daulouède S, Bouteille B, Moynet D, De Baetselier P, Courtois P, Lemesre JL, Buguet A, Cespuglio R, Vincendeau P:
Human macrophage tumor necrosis factor TNF-alpha production induced by Trypanosoma brucei gambiense and the role of TNF-alpha in parasite control
J Infect Dis 183: 988-991
2001
Abstract PubMed
Zhang Z, Bagby GJ, Stoltz D, Oliver P, Schwarzenberger PO, Kolls JK:
Prolonged ethanol treatment enhances lipopolysaccharide/phorbol myristate acetate-induced tumor necrosis factor-alpha production in human monocytic cells
Alcohol Clin Exp Res 25: 444-449
2001
Abstract PubMed
Rinker KD, Prabhakar V, Truskey GA:
Effect of contact time and force on monocyte adhesion to vascular endothelium
Biophys J 80: 1722-1732
2001
Abstract PubMed
Sato K, Akaki T, Shimizu T, Sano C, Ogasawara K, Tomioka H:
Invasion and intracellular growth of Mycobacterium tuberculosis and Mycobacterium avium complex adapted to intramacrophagic environment within macrophages and type II alveolar epithelial cells
Kekkaku 76: 53-57
2001
Abstract PubMed
Cambien B, Pomeranz M, Millet MA, Rossi B, Schmid-Alliana A:
Signal transduction involved in MCP-1-mediated monocytic transendothelial migration
Blood 97(2): 359-366
2001
Abstract PubMed
Cambien B, Pomeranz M, Schmid-Antomarchi H, Millet MA, Breittmayer V, Rossi B, Schmid-Alliana A:
Signal transduction pathways involved in soluble fractalkine-induced monocytic cell adhesion
Blood 97 (7): 2031-2037
2001
Abstract PubMed
Fessele S, Boehlk S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D, Nelson PJ:
Molecular and in silico characterization of a promoter module and C/EBP element that mediate LPS-induced RANTES/CCL5 expression in monocytic cells
FASEB J 15: 577-579
2001
Abstract PubMed
Min HK, Kambe N, Schwartz LB:
Human mouse mast cell protease 7-like tryptase genes are pseudogenes
J Allergy Clin Immunol 107: 315-321
2001
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Ulanova M, Tarkowski A, Hahn-Zoric M, Hanson LA:
The Common vaccine adjuvant aluminum hydroxide up-regulates accessory properties of human monocytes via an interleukin-4-dependent mechanism
Infect Immun 69:1151-1159
2001
Abstract PubMed
Jonas D, Engels I I, Friedhoff C, Spitzmuller B, Daschner FD, Frank U:
Efficacy of moxifloxacin, trovafloxacin, clinafloxacin and levofloxacin against intracellular Legionella pneumophila
J Antimicrob Chemother 47: 147-152
2001
Abstract PubMed
Fettes PS, Susa M, Hacker J, Marre R:
Characterization of the Legionella pneumophila gene ligA
Int J Med Microbiol 290: 239-250
2000
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Howie S, Ramage R, Hewson T:
Innate immune system damage in human immunodeficiency virus type 1 infection. Implications for acquired immunity and vaccine design.
Am J Respir Crit Care Med 162 (4): S141-S145
2000
Abstract PubMed
Rodenburg RJ, Ganga A, van Lent PL, van de Putte LB, van Venrooij WJ:
The antiinflammatory drug sulfasalazine inhibits tumor necrosis factor alpha expression in macrophages by inducing apoptosis
Arthritis Rheum 43: 1941-1950
2000
Abstract PubMed
Scarafia LE, Winter A, Swinney DC:
Quantitative expression analysis of the cellular specificity of HECT-domain ubiquitin E3 ligases
Physiol Genomics 4: 147-153
2000
Abstract PubMed
Lehmann T, Nguyen LQ, Handel ML:
Synovial fluid induced nuclear factor-kappaB DNA binding in a monocytic cell line
J Rheumatol 27: 2769-2776
2000
Abstract PubMed
Udalova IA, Richardson A, Denys A, Smith C, Ackerman H, Foxwell B, Kwiatkowski D:
Functional consequences of a polymorphism affecting NF-kappaB p50-p50 binding to the TNF promoter region
Mol Cell Biol 20: 9113-9119
2000
Abstract PubMed
Vaday GG, Hershkoviz R, Rahat MA, Lahat N, Cahalon L, Lider O:
Fibronectin-bound TNF-alpha stimulates monocyte matrix metalloproteinase-9 expression and regulates chemotaxis
J Leukoc Biol 68: 737-747
2000
Abstract PubMed
Morris RHK, Price AJ, Tonks A, Jackson SK, Jones KP:
Prostaglandin E2 and tumor necrosis factor-alpha release by monocytes are modulated by phospholipides
Cytokine 12: 1717-1719
2000
Abstract PubMed
Pedraza C, Geberhiwot T, Ingerpuu S, Assefa D, Wondimu Z, Kortesmaa J, Tryggvason K, Virtanen I, Patarroyo M:
Monocytic cells synthesize, adhere to, and migrate on laminin-8
J Immunol 165: 5831-5838
2000
Abstract PubMed
Ahmed ST, Ivashkiv LB:
Inhibition of IL-6 and IL-10 signaling and stat activation by inflammatory and stress pathways
J Immunol 165: 5227-5237
2000
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Walz JM, Gerhardt H, Faigle M, Wolburg H, Neumeister B:
Legionella species of different human prevalence induce different rates of apoptosis in human monocytic cells
APMIS 2000 108: 398-408
2000
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Gerhardt H, Walz MJ, Faigle M, Northoff H, Wolburg H, Neumeister B:
Localization of Legionella bacteria within ribosome-studded phagosomes is not restricted to Legionella pneumophila
FEMS Microbiol Lett 192: 145-152
2000
Abstract PubMed
Buehling F, Ittenson A, Kaiser D, Tholert G, Hoffmann B, Reinhold D, Ansorge S, Welte T:
MRP8/MRP14, CD11b and HLA-DR expression of alveolar macrophages in pneumonia
Immunol Lett 71:185-190
2000
Abstract PubMed
Suling WJ, Seitz LE, Pathak V, Westbrook L, Barrow EW, Zywno-Van-Ginkel S, Reynolds RC, Piper JR, Barrow WW:
Antimycobacterial activities of 2,4-diamino-5-deazapteridine derivatives and effects on mycobacterial dihydrofolate reductase
Antimicrob Agents Chemother, 44: 2784-2793
2000
Abstract PubMed
Brown DM, Stone V, Findlay P, MacNee W, Donaldson K:
Increased inflammation and intracellular calcium caused by ultrafine carbon black is independent of transition metals or other soluble components
Occup Environ Med , 57: 685-691
2000
Abstract PubMed
Jonas D, Engels I, Daschner FD, Frank U:
The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivo
J Antimicrob Chemother, 46: 385-390
2000
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Moesby L, Hansen EW, Christensen JD:
Endotoxin testing of proteins for parenteral administration using the Mono Mac 6 assay
J Clin Pharm Ther, 25: 283-289
2000
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Pan Z, Zhou L, Hetherington CJ, Zhang DE:
Hepatocytes contribute to soluble CD14 production and CD14 expression is differentially regulated in hepatocytes and monocytes
J Biol Chem 25; 275(46):36430-5
2000
Abstract PubMed
Strissel PL, Strick R, Tomek RJ, Roe BA, Rowley JD, Zeleznik-Le NJ:
DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis
Hum Mol Genet; 9: 1671-1679
2000
Abstract PubMed
Steube KG, Meyer C, Drexler HG:
Multiple regulation of constitutive and induced interleukin 8 secretion in human myelomonocytic cell lines
Cytokine 12: 1236-1239
2000
Abstract PubMed
Triantafilou M, Triantafilou K, Fernandez N:
Rough and smooth forms of fluorescein-labelled bacterial endotoxin exhibit CD14/LBP dependent and independent binding that is influencedby endotoxin concentration
Eur J Biochem 267: 2218-2226
2000
Abstract PubMed
Udalova IA, Vidal V, Scragg IG, Kwiatkowski D:
Direct Evidence for Involvement of NF-kappaB in Transcriptional Activation of Tumor Necrosis Factor by a Spirochetal Lipoprotein
Infect Immun 68: 5447-5449
2000
Abstract PubMed
Straif D, Werz O, Kellner R, Bahr U, Steinhilber D:
Glutathione peroxidase-1 but not -4 is involved in the regulation of cellular 5-lipoxygenase activity in monocytic cells
Biochem J 349: 455-461
2000
Abstract PubMed
Burgermeister E, Pessara U, Tibes U, Kuster A, Heinrich PC, Scheuer WV:
Inhibition of cytosolic phospholipase A(2) attenuates activation of mitogen-activated protein kinases in human monocytic cells
Eur J Pharmacol 388: 195-208
2000
Abstract PubMed
Moesby L, Hansen EW, Christensen JD:
Ultrasonication of pyrogenic microorganisms improves the detection of pyrogens in the Mono Mac 6 assay
Eur J Pharm Sci 11: 51-57
2000
Abstract PubMed
Tsai EY, Falvo JV, Tsytsykova AV, Barczak AK, Reimold AM, Glimcher LH, Fenton MJ, Gordon DC, Dunn IF, Goldfeld AE:
A lipopolysaccharide-specific enhancer complex involving ets, elk-1, sp1, and CREB binding protein and p300 is recruited to the tumor necrosis factor alpha promoter In vivo
Mol Cell Biol 20: 6084-6094
2000
Abstract PubMed
Zhang Z, Cork J, Ye P, Lei D, Schwarzenberger PO, Summer WR, Shellito JE, Nelson S, Kolls JK:
Inhibition of TNF-alpha processing and TACE-mediated ectodomain shedding by ethanol
Leukoc Biol 67:856-862
2000
Abstract PubMed
Eissner G, Kirchner S, Lindner H, Kolch W, Janosch P, Grell M, Scheurich P, Andreesen R, Holler E:
Reverse Signaling Through Transmembrane TNF Confers Resistance to Lipopolysaccharide in Human Monocytes and Macrophages
J Immunol 164: 6193-6198
2000
Abstract PubMed
Fearns C, Kline L, Gram H, Di Padova F, Zurini M, Han J, Ulevitch RJ:
Coordinate activation of endogenous p38alpha, beta, gamma, and delta by inflammatory stimuli
J Leukoc Biol 67: 705-711
2000
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Werz O, Wiesinger H, Steinmeyer A, Steinhilber D:
New vitamin D receptor agonists with decreased metabolic stability
Biochem Pharmacol, 59:1597-1601
2000
Abstract PubMed
Werz O, Klemm J, Samuelsson B, Radmark O:
5-Lipoxygenase is phosphorylated by p38 kinase-dependent MAPKAP kinases
Proc Natl Acad Sci U S A 97: 5261-5266
2000
Abstract PubMed
Dankesreiter S, Hoess A, Schneider-Mergener J, Wagner H, Miethke T:
Synthetic endotoxin-binding peptides block endotoxin- triggered TNF-alpha production by macrophages In vitro and In vivo and prevent endotoxin-mediated toxic shock
J Immunol 164:4804-4811
2000
Abstract PubMed
van Aken BE, Jansen J, van Deventer SJ, Reitsma PH:
Elevated levels of homocysteine increase IL-6 production in monocytic Mono Mac 6 cells
Blood Coagul Fibrinolysis 11:159-164
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Abstract PubMed
Boehlk S, Fessele S, Mojaat A, Miyamoto NG, Werner T, Nelson EL, Schlondorff D, Nelson PJ:
ATF and Jun transcription factors, acting through an Ets / CRE promoter module, mediate lipopolysaccharide inducibility of the chemokine RANTES in monocytic Mono Mac 6 cells
Eur J Immunol 30:1102-1112
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Abstract PubMed
Zhang Z, Kolls JK, Oliver P, Good D, Schwarzenberger PO, Joshi MS, Ponthier JL, Lancaster JR:
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Eissner G, Lindner H, Konur A, Kreutz M, Andreesen R, Holler E:
Naive monocytes can trigger transendothelial migration of peripheral blood cells through the induction of endothelial tumour necrosis factor-alpha
Scand J Immunol 51: 251-261
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Stone V, Tuinman M, Vamvakopoulos JE, Shaw J, Brown D, Petterson S, Faux SP, Borm P, MacNee W, Michaelangeli F, Donaldson K:
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Eur Respir J 15: 297-303
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Neumeister B, Reiff G, Faigle M, Dietz K, Northoff H, Lang F:
Influence of Acanthamoeba castellanii on Intracellular Growth of Different Legionella Species in Human Monocytes
Appl Environ Microbiol 66: 914-919
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Jones BG, Gumbleton M, Kellaway IW, Dickinson PA:
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Int J Pharm 195: 17-23
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Scragg IG, Kwiatkowski D, Vidal V, Reason A, Paxton T, Panico M, Dell A, Morris H:
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J Biol Chem 275: 937-941
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Tomioka, H., Sato, K., Kajitani, H., Akaki, T., Shishido, S:
Comparative Antimicrobial Activities of the Newly Synthesized Quinolone WQ-3034, Levofloxacin, Sparfloxacin, and Ciprofloxacin against Mycobacterium tuberculosis and Mycobacterium avium Complex
Antimicrob Agents Chemother 44: 283-286
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Abstract PubMed
Heidenthal, A.K., Weber, P.C., Lottspeich, F., Hrboticky, N:
The Binding in Vitro of Modified LDL to the Intermediate Filament Protein Vimentin
Biochem Biophys Res Commun 267: 49-53
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Abstract PubMed
Benkhart EM, Siedlar M, Wedel A, Werner T, Ziegler-Heitbrock HW:
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J Immunol 165: 1612-1617
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Sironi M, Guglielmotti A, Polentarutti N, Fioretti F, Milanese C, Romano M, Vigini C, Coletta I, Sozzani S, Bernasconi S, Vecchi A, Pinza M, Mantovani A:
A small synthetic molecule capable of preferentially inhibiting the production of the CC chemokine monocyte chemotactic protein-1
Eur Cytokine Netw 10: 437-442
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Riehemann K, Behnke B, Schulze-Osthoff K:
Plant extracts from stinging nettle (Urtica dioica), an antirheumatic remedy, inhibit the proinflammatory transcription factor NF-kappaB
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Burkart V, Kim Y, Kauer M, Kolb H:
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1H-cyclopenta[b]benzofuran lignans from Aglaia species inhibit cell proliferation and alter cell cycle distribution in human monocytic leukemia cell lines
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Haerle D, Radmark O, Samuelsson B, Steinhilber D:
Transcriptional and posttranscriptional regulation of 5-lipoxygenase mRNA expression in the human monocytic cell line Mono Mac 6 by transforming growth factor-beta and 1,25-dihydroxyvitamin D3
Adv Exp Med Biol 469: 105-111
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Valen, G., Erl, W., Eriksson, P., Wuttge, D., Paulsson, G., Hansson, G.K:
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Free Radic Res 31: 503-512
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Watts, A.D., Hunt, N.H., Madigan, M.C., Chaudhri, G:
Soluble TNF-alpha receptors bind and neutralize over-expressed transmembrane TNF-alpha on macrophages, but do not inhibit its processing
J Leukoc Biol 66:1005-1013
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van Zandbergen, G., Westerhuis, R., Mohamad, N.K., van De Winkel, J.G., Daha, M.R., van Kooten, C.:
Crosslinking of the Human Fc Receptor for IgA (FcalphaRI/CD89) Triggers FcR gamma-Chain-Dependent Shedding of Soluble CD89
J Immunol 163: 5806-5812
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Abstract PubMed
Moesby L., Jensen S., Hansen E.W., Christensen J.D.:
A comparative study of Mono Mac 6 cells, isolated mononuclear cells and Limulus amoebocyte lysate assay in pyrogen testing
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Pan, Z., Hetherington, C.J., Zhang, D.E:
CCAAT/enhancer-binding protein activates the CD14 promoter and mediates transforming growth factor beta signaling in monocyte development
J Biol Chem, 274: 23242-2328
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Lorenzen, D.R., Dux, F., Wolk, U., Tsirpouchtsidis, A., Haas, G., Meyer, T.F:
Immunoglobulin A1 protease, an exoenzyme of pathogenic neisseriae, is a potent inducer of proinflammatory cytokines
J Exp Med, 190: 1049-1058
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Trautmann, M., Heinemann, M., Moricke, A., Seidelmann, M., Lorenz, I., Berger, D., Steinbach, G., Schneider, M:
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J Chemother, 11: 248-254
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Grone, H.J., Weber, C., Weber, K.S., Grone, E.F., Rabelink, T., Klier, C.M., Wells, T.N., Proudfood, A.E., Schlondorff, D., Nelson, P.J:
Met-RANTES reduces vascular and tubular damage during acute renal transplant rejection: blocking monocyte arrest and recruitment
FASEB J, 13: 1371-1383
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Vraetz, T., Ittel, T.H., van Mackelenbergh, M.G., Heinrich, P.C., Sieberth, H.G., Graeve, L:
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Nephrol Dial Transplant, 14: 2137-2143
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Abstract PubMed
Scragg, I.G., Hensmann, M., Bate, C.A., Kwiatkowski, D:
Early cytokine induction by Plasmodium falciparum is not a classical endotoxin-like process
Eur J Immunol, 29: 2636-2644
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Abstract PubMed
Bakker, A.B., Baker, E., Sutherland, G.R., Phillips, J.H., Lanier, L.L:
Myeloid DAP12-associating lectin (MDL)-1 is a cell surface receptor involved in the activation of myeloid cells
Proc Natl Acad Sci U S A, 17: 9792-9796
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Penton-Rol, G., Cota, M., Polentarutti, N., Luini, W., Bernasconi, S., Borsatti, A., Sica, A., LaRosa, G.J., Sozzani, S., Poli, G., Mantovani, A:
Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones
J. Immunol., 163: 3524-3529
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Abstract PubMed
Steube, K.G., Meyer, C., Drexler, H.G:
Constitutive protein expression of monocyte chemotactic protein-1 (MCP-1) by myelomonocytic cell lines and regulation of the secretion by anti- and proinflammatory stimuli
Leuk. Res., 23:843-849
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Abstract PubMed
Sato, K., Ogasawara, K., Akaki, T., Tomioka, H:
MICs and MBCs of levofloxacin, clarithromycin, and KRM-1648 for Mycobacterium tuberculosis and M. avium complex residing in MONO-MAC-6 human macrophage-like cell and A-549 human type II alveolar epithelial cell lines
Kekkaku, 74: 571-577
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Abstract PubMed
Curiel, R.E., Garcia, C.S., Rottschafer, S., Bosco, M.C., Espinoza-Delgado, I:
Enhanced B7-2 Gene Expression by Interferon- in Human Monocytic Cells Is Controlled Through Transcriptional and Posttranscriptional Mechanisms
Blood, 94: 1782-1789
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Abstract PubMed
Jansen, M., Reinhard, J.F. Jr:
Interferon response heterogeneity: activation of a pro-inflammatory response by interferon alpha and beta. A possible basis for diverse responses to interferon beta in MS.
J. Leukoc. Biol., 65:439-443
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Berg, J., Fellier, H., Christoph, T., Grarup, J., Stimmeder, D:
The analgesic NSAID lornoxicam inhibits cyclooxygenase (COX)-1/-2, inducible nitric oxide synthase (iNOS), and the formation of interleukin (IL)-6 in vitro
Inflamm. Res., 48:369-379
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Abstract PubMed
Weber, C., Draude, G., Weber, K.S., Wubert, J., Lorenz, R.L., Weber, P.C:
Downregulation by tumor necrosis factor-alpha of monocyte CCR2 expression and monocyte chemotactic protein-1-induced transendothelial migration is antagonized by oxidized low-density lipoprotein: a potential mechanism of monocyte retention in atherosclero
Atherosclerosis145:115-123
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Abstract PubMed
Musso, T., Calosso, L., Zucca, M., Millesimo, M., Ravarino, D., Giovarelli, M., Malavasi, F., Ponzi, A.N., Paus, R., Bulfone-Paus, S:
Human monocytes constitutively express membrane-bound, biologically active, and interferon-gamma-upregulated interleukin-15
Blood 93: 3531-3539
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Abstract PubMed
Iwama, A., Pan, J., Zhang, P., Reith, W., Mach, B., Tenen, D.G., Sun, Z.:
Dimeric RFX proteins contribute to the activity and lineage specificity of the interleukin-5 receptor alpha promoter through activation and repression domains
Mol Cell Biol, 19:3940-3950
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Abstract PubMed
Weber, K.S., Draude, G., Erl, W., de Martin, R., Weber, C.:
Monocyte arrest and transmigration on inflamed endothelium in shear flow is inhibited by adenovirus-mediated gene transfer of IkappaB-alpha
Blood, 93:3685-3693
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Abstract PubMed
Karimi, K., Gemmill, T.R., Lennartz, M.R.:
Protein kinase C and a calcium-independent phospholipase are required for IgG-mediated phagocytosis by Mono-Mac-6 cells
J. Leukoc. Biol. 65: 854-862
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Abstract PubMed
Knight, J.C., Udalova, I., Hill, A.V., Greenwood, B.M., Peshu ,N., Marsh, K., Kwiatkowski, D.:
A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria
Nat Genet 22: 145-150
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Bonder, C.S., Finlay-Jones, J.J., Hart, P.H.:
Interleukin-4 regulation of human monocyte and macrophage interleukin-10 and interleukin-12 production. Role of a functional interleukin-2 receptor gamma-chain.
Immunology 96: 529-536
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Musso, T., Calosso, L., Zucca, M., Millesimo, M., Ravarino, D., Giovarelli, M., Malavasi, F., Ponzi, A.N., Paus, R., Bulfone-Paus S.:
Human Monocytes Constitutively Express Membrane-Bound, Biologically Active, and Interferon-gamma-Upregulated
Interleukin-15. Blood 93: 3531-3539
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Abstract PubMed
Bohnenstengel, F.I., Steube, K.G., Meyer, C., Nugroho, B.W., Hung, P.D., Kiet, L.C., Proksch, P.:
Structure activity relationships of antiproliferative rocaglamide derivatives from Aglaia species (Meliaceae)
Z Naturforsch [C] 54: 55-60
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Chen W, Syldath U, Bellmann K, Burkart V, Kolb H:
Human 60-kDa heat-shock protein: a danger signal to the innate immune system
J Immunol 162: 3212-3219
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Sato K, Tomioka H:
In vitro antimicrobial activities of quinolones, rifamycins and macrolides against Mycobacterium tuberculosis and M. avium complex: attempt to establish new assay methods which accurately reflect therapeutic effects of test agents in vivo
Kekkaku 74: 63-70
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Engelmann B, Zieseniss S, Brand K, Page S, Lentschat A, Ulmer AJ, Gerlach E:
Tissue factor expression of human monocytes is suppressed by lysophosphatidylcholine
Arterioscler Thromb Vasc Biol 19: 47-53
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Abstract PubMed
Hamik A, Setiadi H, Bu G, McEver RP, Morrissey JH:
Down-regulation of monocyte tissue factor mediated by tissue factor pathway inhibitor and the low density lipoprotein receptor-related protein
J Biol Chem 274: 4962-4969
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Zughaier SM, Ryley HC, Jackson SK:
A melanin pigment purified from an epidemic strain of Burkholderia cepacia attenuates monocyte respiratory burst activity by scavenging superoxide anion
Infect Immun 67(2): 908-913
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Abstract PubMed
Zughaier SM, Ryley HC, Jackson SK:
Lipopolysaccharide (LPS) from Burkholderia cepacia is more active than LPS from Pseudomonas aeruginosa and Stenotrophomonas maltophilia in stimulating tumor necrosis factor a
Infect Immun 67(3): 1505-1507
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Howie SE, Fernandez ML, Heslop I, Hewson TJ, Cotton GJ, Moore MJ, Innes D, Ramage R, Harrison DJ:
A functional, discontinuous HIV-1 gp120 C3/C4 domain-derived, branched, synthetic peptide that binds to CD4 and inhibits MIP-1alpha chemokine binding
FASEB J 13: 503-511
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Page S, Fischer C, Baumgartner B, Haas M, Kreusel U, Loidl G, Hayn M, Ziegler-Heitbrock HW, Neumeier D, Brand K:
4-Hydroxynonenal Prevents NF-kappaB Activation and Tumor Necrosis Factor Expression by Inhibiting IkappaB Phosphorylation and Subsequent Proteolysis
J Biol Chem 274(17): 11611-11618
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Kastenbauer S, Ziegler-Heitbrock H W:
NF-kappaB1 (p50) is upregulated in lipopolysaccharide tolerance and can block tumor necrosis factor gene expression
Infect Immun 67: 1553-91
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Vidal V, Scragg IG, Cutler SJ, Rockett KA, Fekade D, Warrell DA, Wright DJ, Kwiatkowski D:
Variable major lipoprotein is a principal TNF-inducing factor of louse-borne relapsing fever
Nat Med 4: 1416-1420
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Prasad, N.K., Papoff, G., Zeuner, A., Bonnin, E., Kazatchkine, M.D., Ruberti, G., Kaveri, S.V:
Therapeutic preparations of normal polyspecific IgG (IVIg) induce apoptosis in human lymphocytes and monocytes: a novel mechanism of action of IVIg involving the Fas apoptotic pathway
J Immunol; 161:3781-3790
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Finstad, H.S., Myhrstad, M.C., Heimli, H., Lomo, J., Blomhoff, H.K., Kolset, S.O., Drevon, C.A:
Multiplication and death-type of leukemia cell lines exposed to very long-chain polyunsaturated fatty acids
Leukemia, 12:921-929
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Kato, M., Neil, T.K., Clark, G.J., Morris, C.M., Sorg, R.V., Hart, D.N.J:
cDNA cloning of human DEC-205, a putative antigen-uptake receptor on dendritic cells
Immunogenetics 47:442-450
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Mahony D, Stringer BW, Dickinson JL, Antalis TM:
DNase I hypersensitive sites in the 5' flanking region of the human plasminogen activator inhibitor type 2 (PAI-2) gene are associated with basal and tumor necrosis factor-alpha-induced transcription in monocytes
Eur J Biochem 256: 550-559
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Gidlof C, Carlson B, Dohlsten M, Totterman TH:
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Eur J Haematol 60: 233-239
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Bergmann S, Siekmeier R, Mix C, Jaross W:
Even moderate cigarette smoking influences the pattern of circulating monocytes and the concentration of sICAM-1
Respir Physiol 114: 269-275
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Strissel PL, Strick R, Rowley JD, Zeleznik-Le NJ:
An in vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region
Blood 92: 3793-3803
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Sengupta, T.K., Talbot, E.S., Scherle, P.A., Ivashkiv, L.B.:
Rapid inhibition of interleukin-6 signaling and Stat3 activation mediated by mitogen-activated protein kinases
Proc. Natl. Acad. Sci. USA 95: 11107-11112
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Melkonyan, H., Hofmann, H.A., Nacken, W., Sorg, C., Klempt, M.:
The gene encoding the myeloid-related protein 14 (MRP14), a calcium-binding protein expressed in granulocytes and monocytes, contains a potent enhancer element in the first intron
J. Biol. Chem. 273: 27026-27032
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Barrow, E.L.W., Winchester, G.A., Staas, J.K., Quenelle, D.C., Barrow, W.W.:
Use of microsphere technology for targeted delivery of rifampin to Mycobacterium tuberculosis-infected macrophages
Antimicrob. Agents Chemother. 42: 2682-22689
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Lodie, T.A., Reiner, M., Coniglio, S., Viglianti, G., Fenton, M.J.:
Both PU.1 and nuclear factor-kappa B mediate lipopolysaccharide- induced HIV-1 long terminal repeat transcription in macrophages.
J. Immunol. 161: 268-276
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Neumeister, B., Faigle, M., Sommer, M., Zahringer, U., Stelter, F., Menzel, R., Schutt, C., Northoff, H.:
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Infect. Immun. 66: 4151-4157
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Udalova, I.A., Knight, J.C., Vidal, V., Nedospasov, S.A., Kwiatkowski, D.:
Complex NF-kappaB interactions at the distal Tumor Necrosis Factor promoter region in human monocytes
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Weber, K.S., Klickstein, L.B., Weber, P.C., Weber, C.:
Chemokine-induced monocyte transmigration requires cdc42-mediated cytoskeletal changes
Eur. J. Immunol. 28: 2245-2251
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Darke, B.M., Jackson, S.K., Hanna, S.M., Fox, J.D.:
Detection of human TNF-alpha mRNA by NASBA
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Schneitler, C., Kahler, C., Wiedermann, C.J., Hogue-Angeletti, R., Fischer-Colbrie, R.:
Specific binding of a 125I-secretoneurin analogue to a human monocytic cell line
J. Neuroimmunol. 86: 87-91
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Haerle, D., Radmark, O., Samuelsson, B., Steinhilber, D.:
Calcitriol and transforming growth factor-beta upregulate 5-lipoxygenase mRNA expression by increasing gene transcription and mRNA maturation
Eur. J. Biochem. 254: 275-281
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Antalis, T.M., La Linn, M., Donnan, K., Mateo, L., Gardner, J., Dickinson, J.L., Buttigieg, K., Suhrbier, A.:
The serine proteinase inhibitor (serpin) plasminogen activation inhibitor type 2 protects against viral cytopathic effects by constitutive interferon alpha/beta priming
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Dreier, J., Högger, P., Sorg, C.:
Rapid method for isolation of total RNA from eukaryotic cell lines and leukocytes
DNA Cell Biol. 17: 321-323
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Steube, K.G., Meyer, C., Proksch, P., Supriyono, A., Sumaryono, W., Drexler, H.G.:
A new calyculin derivative from the sponge Theonella swinhoei is a novel and potent inhibitor of tumor cell proliferation
Anticancer Research 18: 129-137
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Bonder, C.S., Dickensheets, H.L., Finlay-Jones, J.J., Donnelly, R.P., Hart, P.H.:
Involvement of the IL-2 receptor gamma-chain (gammac) in the control by IL-4 of human monocyte and macrophage proinflammatory mediator production
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Landmann, R., Link, S., Sansano, S., Rajacic, Z., Zimmerli, W.:
Soluble CD14 activates monocytic cells independently of Lipopolysaccharide
Infect. Immun. 66: 2264-2271
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Sprong, R.C., Winkelhuyzen-Janssen, A.M.L., Aarsman, C.J.M., van Oirschot, J.F.L.M., van der Bruggen, T., Sweder van Asbeck, B.:
Low-dose N-Acetylcysteine protects Rats against Endotoxin-mediated Oxidative Stress, but High-dose increases Mortality
Am. J. Respir. Crit. Care Med. 157: 1283-1293
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Eder, C., Schupp, P., Proksch, P., Wray, V., Steube, K., Müller, C.E., Frobenius, W., Herderich, M., van Soest, R.W.M.:
Bioactive pyridoacridine alkaloids from the micronesian sponge Oceanapia sp
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Neumeister, B., Kleihauer, A., Rossmann, V., Fehrenbach, E., Faigle, M., Baumbach, S., Northoff, H.:
Induction of cytokines and expression of surface receptors in Mono Mac 6 cells after infection with different Legionella species
APMIS 106: 319-333
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Erl, W., Weber, P.C., Weber, C.:
Monocytic cell adhesion to endothelial cells stimulated by oxidized low density lipoprotein is mediated by distinct endothelial ligands
Atherosclerosis 136: 297-303
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Åbrink, M., Larsson, E., Hellman, L.:
Demethylation of ERV3, an endogenous retrovirus regulating the Krüppel-related zinc finger gene H-plk, in several human cell lines arrested during early monocyte development
DNA Cell Biol. 17: 27-37
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Kaijzel EL, van Krugten MV, Brinkman BM, Huizinga TW, van der Straaten T, Hazes JM, Ziegler-Heitbrock HW, Nedospasov SA, Breedveld FC, Verweij CL:
Functional analysis of a human tumor necrosis factor alpha (TNF-alpha) promoter polymorphism related to joint damage in rheumatoid arthritis
Mol Med 4: 724-33
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Werz, O., Schneider, N., Brungs, M., Sailer, E.R., Safayhi, H., Ammon, H.P., Steinhilber, D.:
A test system for leukotriene synthesis inhibitors based on the in-vitro differentiation of the human leukemic cell lines HL-60 and Mono Mac 6
Naunyn Schmiedebergs Arch Pharmacol, 356:441-445
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Machein, U., Conca, W.:
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Tangirala, R.K., Murao, K., Quehenberger, O.:
Regulation of expression of the human monocyte chemotactic protein-1 receptor (hCCR2) by cytokines
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Moesby, L., Hansen, E.W., Dencker, J.:
Pyrogen testing of lipid-based TPN using Mono Mac 6 monocyte cell line and DELFIA
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Loiseau, P.M., Dreyfuss, G., Daulouède, S., Lachâtre, G., Vincendeau, P., Craciunescu, D.G.:
Trypanocidal effect of Ir-(COD)-pentamidine tetraphenylborate on Trypanosoma brucei and T. b. gambiense rodent models and serum kinetics in sheep.
Trop. Med. Int. Health 2: 19-27
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Merk, H.F., Baron, J., Hertl, M., Niederau, D., Rübben, A.:
Lymphocyte activation in allergic reactions elicited by small-molecular-weight compounds
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Hrboticky, N., Becker, A., Kruse, H.J., Weber, P.C.:
Increased cellular triglyceride levels in human monocytic and rat smooth muscle cells after lovastatin
Biochimica et Biophysica Acta - Lipids and Lipid Metabolism 1349: 211-221
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Bussfeld, D., Bacher, M., Moritz, A., Gemsa, D., Sprenger, H.:
Expression of transcription factor genes after influenza A virus infection
Immunobiology, 198: 291-298
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Joyce, D.A., Kloda, A., Steer, J.H.:
Dexamethasone suppresses release of soluble TNF receptors by human monocytes concurrently with TNF-a suppression
Immunol. Cell Biol., 75: 345-350
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Tenno, T., Botling, J., Öberg, F., Nilsson, K., Siegbahn, A.:
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Thrombosis Research, 88: 215-228
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Eperon, S., De Groote, D., Werner-Felmayer, G., Jungi, T.W.:
Human monocytoid cell lines as indicators of endotoxin: comparison with rabbit pyrogen and Limulus amoebocyte lysate assay
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Super, H.G., Strissel, P.L., Sobulo, O.M., Burian, D., Reshmi, S.C., Roe, B., Zeleznik-Le, N.J., Diaz, M.O., Rowley, J.D.:
Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia
Genes Chromosomes Cancer, 20: 185-195
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Cross, A.K., Richardson, V., Ali, S.A., Palmer, I., Taub, D.D., Rees, R.C.:
Migration responses of human monocytic cell lines to a- and b-chemokines
Cytokine, 9: 521-528
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Pedron, T., Girard, R., Inoue, K., Charon, D., Chaby, R.:
Lipopolysaccharide and the glycoside ring of staurosporine induce CD14 expression on bone marrow granulocytes by different mechanisms
Molecular Pharmacology, 52: 692-700
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Hetland, G.:
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Anti Cancer Drugs, 8: 618-622
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Berg, J., Christoph, T., Widerna, M., Bodenteich, A.:
Isoenzyme specific cyclooxygenase inhibitors: a whole cell assay system using the human erythroleukemic cell line Hel and the human monocytic cell line Mono Mac 6
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Reischl, I.G., Corvaia, N., Unger, J., Woisetschläger, M., Mudde, G.C.:
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Scheithe, R., Heidenthal, A.K., Danesch, U., Mauthner, E., Hapfelmeier, G., Becker, A., Pietsch, A., Weber, P.C., Hrboticky, N.:
Acetylated LDL endocytosis by the human monocytic mono mac 6SR cells is not mediated by the macrophage type I and II scavenger receptors
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Troelstra, A., Antal-Szalmas, P., de Graaf-Miltenburg, L.A.M., Weersink, A.J.L., Verhoef, J., Van Kessel, K.P.M., Van Strijp, J.A.G.:
Saturable CD14-dependent binding of fluorescein-labeled lipopolysaccharide to human monocytes
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Cytokine, 8: 335-341
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Expression of a mast cell tryptase in the human monocytic cell lines U-937 and Mono Mac 6
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Abstract PubMed
Friedland, J.S., Shattock, R.J., Griffin, G.E.:
Phagocytosis of Mycobacterium tuberculosis or particulate stimuli by human monocytic cells induces equivalent monocyte chemotactic protein-1 gene expression
Cytokine, 5: 150-156
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Abstract PubMed
Neustock, P., Brand, J.M., Kruse, A., Kirchner, H.:
Cytokine production of the human monocytic cell line Mono Mac 6 in comparison to mature monocytes in peripheral blood mononuclear cells
Immunobiol., 188: 293-302
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Abstract PubMed
Labeta, M.O., Durieux, J.-J., Fernandez, N., Herrmann, R., Ferrara, P.:
Release from a human monocyte-like cell line of two different soluble forms of the lipopolysaccharide receptor, CD14
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Abstract PubMed
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An automated micro-fluorometric assay for monitoring oxidative burst activity of phagocytes
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Abstract PubMed
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Abstract PubMed
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Expression of the monocyte-specific esterase gene in leukemia-lymphoma cell lines
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Abstract PubMed
Gessl, A., Willheim, M., Agis, H., Spittler, A., Schedle, A., Krugluger, W., Förster, O., Boltz-Nitulescu, G.:
Tumour necrosis factor augments the expression of Fc IgE receptor (FceRII/CD23) on human monocytic cell lines and down-regulates interleukin-4-driven FceRII expression on monocytes
Immunol., 78: 476-481
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Abstract PubMed
Ziegler-Heitbrock, H.W.L., Sternsdorf, T., Liese, J., Belohradsky, B., Weber, C., Wedel, A., Schreck, R., Bäuerle, P., Ströbel, M.:
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Abstract PubMed
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Tumor necrosis factor induces enhanced responses to platelet activating factor and differentiation in human monocytic Mono Mac 6 cells
Eur. J. Immunol., 23:852-859
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Abstract PubMed
Thieblemont, N., Haeffner-Cavaillon, N., Ledur, A., L'age-Stehr, J., Ziegler-Heitbrock, H.W.L., Kazatchkine, M.D.:
CR1 (CD35) and CD3 (CD11b/CD18) mediate infection of human monocytes and monocytic cell lines with complement-opsonized HIV independently of CD4
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Abstract PubMed
Lin, S.L., Derr, D., Hildreth, J.E.:
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Abstract PubMed
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Specific inhibition of mRNA accumulation for lymphokines in human T cell line Jurkat by mycobacterial lipoarabinomannan antigen
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Abstract PubMed
Schreck, R., Bevec, D., Dukor, P., Baeuerle, P.A., Chedid, L., Bahr, G.M.:
Selection of a muramyl peptide based on its lack of activation of nuclear factor-kB as a potential adjuvant for AIDS vaccines
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Abstract PubMed
Pradines-Figueres, A., Raetz, R.H.:
Processing and secretion of tumor necrosis factor a in endotoxin-treated Mono Mac 6 cells are dependent on phorbol myristate acetate
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Abstract PubMed
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Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions
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Abstract PubMed
Friedland, J.S., Remick, D.G., Shattock, R., Griffin, G.E.:
Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines
Eur. J. Immunol., 22: 1373-1378
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Abstract PubMed
Haas, J.G., Ströbel, M., Leutz, A., Wendelgaß, P., Müller, C., Sterneck, E., Riethmüller, G., Ziegler-Heitbrock, H.W.L.:
Constitutive monocyte-restricted activity of NF-M, a nuclear factor that binds to a C/EBP motif
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Abstract PubMed
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Abstract PubMed
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Abstract PubMed
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In vitro desensitization to lipopolysaccharides suppresses TNF, IL-1 and IL-6 gene expression in a similar fashion
Immunology, 75: 264-268
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Abstract PubMed
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Cyclic nucleotides differentially regulate the synthesis of tumour necrosis factor-a and interleukin-1b by human mononuclear cells
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Abstract PubMed
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IL-6 augments Fc IgE receptor (FceRII/CD23) expression on human monoblastic/monocytic cell lines U937, THP-1, and Mono Mac 6, but not on blood monocytes
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Abstract PubMed
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Assay of pyrogens by interleukin-6 release from monocytic cell lines
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Abstract PubMed
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Ciprofloxacin enhances T cell function by modulating interleukin activities
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Abstract PubMed
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Expression of a human cytomegalovirus receptor correlates with infectibility of cells
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Abstract PubMed
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Measurement of cytokine production by the monocytic cell line Mono Mac 6 using novel immunoradiometric assays for interleukin-1ß and interleukin-6
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Abstract PubMed
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Infection of the human monocyte cell line Mono Mac 6 with HIV-1 and -2 results in long term production of virus variants with increased virulence for CD4+ T cells
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Abstract PubMed
Haas, J.G., Bäuerle, P.A., Riethmüller, G., Ziegler-Heitbrock, H.W.L.:
Molecular mechanism in down regulation of TNF expression
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Abstract PubMed
Haas, J.G., Meyer, N., Ziegler-Heitbrock, H.W.L.:
Inhibition of lipopolysaccharide-induced in-vitro desensitization by interferon y
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Abstract PubMed
Haas, J.G., Thiel, C., Blömer, K., Weiss, E.H., Riethmüller, G., Ziegler-Heitbrock, H.W.L:
Downregulation of tumor necrosis factor expression in the human Mono-Mac-6 cell line by lipopolysaccharide
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Abstract PubMed
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Establishment of a human cell line (Mono Mac 6) with characteristics of mature monocytes
Int. J. Cancer, 41:456-461
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Abstract PubMed