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slanDCs in carcinoma-draining lymph nodes.

Abstract

Dendritic cells (DCs) are known to initiate adaptive immune responses against malignant cells. However, the role in anticancer immunosurveillance of 6-sulfo LacNAc-expressing DCs (slanDCs), a distinct population of circulating and tissue-resident pro-inflammatory DCs, is unclear. We have recently demonstrated the involvement of slanDCs in nodal immune responses against carcinoma cells.

Authors: Vermi W, Lonardi S, Bugatti M, Calzetti F, Micheletti A, Cassatella MA.
Journal: Oncoimmunology. 2014 Jan 1;3(3):e28246
Year: 2014
PubMed: Find in PubMed